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Published: Dec. 9, 2022. Version: 1.0.0

Soni, S., & Roberts, K. (2022). RadQA: A Question Answering Dataset to Improve Comprehension of Radiology Reports (version 1.0.0). PhysioNet. https://doi.org/10.13026/ckkp-6y19.

Soni, S., Gudala, M., Pajouhi, A., & Roberts, K. (2022, June). RadQA: A Question Answering Dataset to Improve Comprehension of Radiology Reports. In Proceedings of the Thirteenth Language Resources and Evaluation Conference (pp. 6250-6259).

Goldberger, A., Amaral, L., Glass, L., Hausdorff, J., Ivanov, P. C., Mark, R., ... & Stanley, H. E. (2000). PhysioBank, PhysioToolkit, and PhysioNet: Components of a new research resource for complex physiologic signals. Circulation [Online]. 101 (23), pp. e215–e220.

## Background

Machine reading comprehension (MRC) has been widely explored to better comprehend unstructured text, by enabling machines to answer specific questions given a textual passage [1]. Much of these pursuits are powered by neural models and since a well-constructed dataset is pivotal to building a suitable model (for a given requirement, domain, or task) there is an explosion of MRC datasets in recent years [2]. However, little work is drawn toward the clinical domain to build challenging MRC datasets for improving comprehension of the semantically complex and diverse electronic health record (EHR) data.

The current MRC datasets for unstructured EHR data fall short of many important considerations in order to build an advanced model for the task. Most of these datasets are too small (to build advanced models) [3] or publicly unavailable (making them nonexistent for building any models) [4] or both [5,6]. Additionally, the questions for most of these datasets are collected in a manner that induces bias and does not reflect real-world user needs, including for an available dataset where the users are shown candidate questions (with answers) for reference [7]. Lastly, one of the “large” EHR MRC datasets, emrQA [8], has gained much traction. However, the variety in emrQA is severely limited due to templatization, as is also found in a separate systematic analysis of emrQA’s MRC data. Furthermore, almost all existing datasets for EHR MRC use discharge summaries as documents. However, other types of clinical texts such as radiology reports (that have vastly different semantic content and vocabulary) are markedly underrepresented in the MRC task.

We propose RadQA, a new EHR MRC dataset, that aims to overcome the issues with the existing resources for the MRC task in the clinical domain. The questions reflect the true information needs of clinicians ordering radiology reports (as the queries are inspired by the clinical referral section of the radiology reports). The answers are oftentimes present in the form of phrases or span multiple lines (as opposed to only multi-word answer entities in available MRC datasets), fulfilling the clinical information needs. The questions require a wide variety of reasoning and domain knowledge to answer, which makes it a challenging dataset for training advanced models

## Methods

### Document Sampling

We source the radiology reports (used as documents) for our dataset from the MIMIC-III database [9]. We sample a realistic set of reports by selecting the documents at the patient level, i.e., we first sampled 100 patients and then included all the 1009 associated radiology reports in our dataset for annotations. We further divide our data of 100 patients into training, development, and testing splits in the ratio of 8:1:1, respectively.

### Question Creation

The ordering physicians include their requirements in the form of a clinical referral that is sent to the radiologist along with the radiographs. The annotators were asked to create questions thinking about both implicit and explicit information needs expressed by the referral section. Our annotators possess the medical knowledge to understand both the types of information needs in the referral and thus were able to incorporate those needs into their created questions.

Two annotators independently constructed questions for all the reports in our dataset. All the questions are associated with the report whose clinical referral section was used while constructing them. Finally, the questions are deduplicated at the report level.

For marking answers, the annotators were shown the whole radiology report (including the referral) along with the corresponding set of questions. There are two main sections in radiology reports, namely, Findings and Impressions. We tasked the annotators to annotate answer spans in the report text, at most one span each in the Findings and Impressions sections. We instructed them to annotate the shortest possible span that answers a question to the point. Specifically, the selected answer span should be sufficient by itself to answer the question but, simultaneously, it should not contain any additional information that is not required by the question.

Because the questions are not constructed after viewing the full report text or deciding an answer in advance, they may not have direct answers in the report. Further, owing to the question creation phase, all the questions in our dataset are not required to have answers in the report. All the answers are marked by two annotators independently and reconciled at regular intervals.

### Reconciliation

We adjudicated the annotated answers frequently in order to ensure the quality of our dataset. For the first 100 reports, we reconciled in batches of 10, giving both annotators sufficient time to ramp up on the annotation scheme. Afterward, we reconciled in batches of 100 reports. We calculate inter-annotator agreement using the F1 measure.

We reconciled all the answer spans down to one unique answer for our training split. For the dev and test splits, however, as long as both the annotated spans answered the question at hand, we kept both answers in the dataset. This facilitates a natural development and evaluation of models which respects the presence of more than one way of answering a question

## Data Description

### Example

The following is an example report in the dataset with a question and its answers in both the Findings and Impressions sections of Radiology Reports.

#### Findings Section

Context:

FINAL REPORT

INDICATION: XX year old male with status post recent STE MI. Now with increasing edema and shortness of breath.

AP supine single view of the chest is compared to [**2101-3-24**].

FINDINGS: The heart is enlarged in size but stable in the interval. Mediastinal contour is unchanged. There is upper zone redistribution of the pulmonary artery vasculature. Perihilar haziness as well as diffuse bilateral pulmonary opacities. These findings are consistent with acute CHF. There are also bilateral pleural effusions. There is barium in the left colon from previous contrast study.

Question:

Did the cardiac silhouette enlarge?

enlarged in size

221

#### Impressions Section

Context:

IMPRESSION: 1. Findings consistent with pulmonary edema due to CHF. 2. Bilateral pleural effusions.

Question:

Did the cardiac silhouette enlarge

Not applicable

### Format

The dataset is formatted as a json file which follows the structure of SQuAD, a popular open-domain MRC dataset. The following excerpt from the dataset file contains annotations for the above example question-answer pairs.

{
"data": [
{
"paragraphs": [
{
"qas": [
{
"question": "Did the cardiac silhouette enlarge?",
"id": "822252_1_3_O",
{
"text": "enlarged in size",
}
],
"is_impossible": false
}
],
"context": "FINAL REPORT\n INDICATION: XX year old male with status post recent STE MI. Now with\n increasing edema and shortness of breath.\n\n AP supine single view of the chest is compared to [**2101-3-24**].\n\n FINDINGS: The heart is enlarged in size but stable in the interval.\n Mediastinal contour is unchanged. There is upper zone redistribution of the\n pulmonary artery vasculature. Perihilar haziness as well as diffuse bilateral\n pulmonary opacities. These findings are consistent with acute CHF. There are\n also bilateral pleural effusions. There is barium in the left colon from\n previous contrast study.",
"document_id": "822252_O"
},
{
"qas": [
{
"question": "Did the cardiac silhouette enlarge?",
"id": "822252_1_3_I",

],
"is_impossible": true
}
],
"context": "IMPRESSION: 1. Findings consistent with pulmonary edema due to CHF. 2.\n Bilateral pleural effusions.",
"document_id": "1053165_I"
}
],
"title": "1053165"
}
],
"version": "1.0.0"
}

### Files

The dataset is split into training, development, and testing sets at the patient level (in the ratio of 8:1:1) for a realistic evaluation. The following files are included.

• train.json - training set
• dev.json - development set
• test.json - testing set

### Statistics

The descriptive statistics of the sampled radiology reports and those in MIMIC-III (after removing outlier patients) are presented below. The top modalities are determined separately after filtering out the report types with proportions less than 0.1%.

# of patients 100 34,325
# of reports 1009 332,922
Avg reports per patient 10.09 9.7
Std of reports per patient 8.15 8.33
Median reports per patient 7.5 7
Top five modalities (proportion in %)
X-ray 59.76 55.32
Computed Tomography (CT) 14.37 16.23
Ultrasound (US) 5.15 4.61
Magnetic Resonance (MR) 3.87 4.31
CT Angiography (CTA) 2.38 2.43

Following are the descriptive statistics of RadQA (with emrQA for comparison). Lengths are in tokens. UnAns – Unanswerable. Med – Median.

# of paragraphs   1009 303
# of questions Total 6148 73,111
UnAns 1754 --
Ques per para Avg 6.09 241.29
Med 6 215
Paragraph len Avg 274.49 1394.29
Med 207 1208
Question len Avg 8.56 9.40
Med 8 9
Med 7 2

## Usage Notes

The RadQA dataset can be used to train machine comprehension models to enable answering a question given a radiology report text. The dataset contains predefined training, development, and testing splits, making it easier to compare the results.

## Ethics

The authors have no ethical concerns to declare.

## Acknowledgements

This work was supported by the U.S. National Library of Medicine, National Institutes of Health, (R00LM012104); the National Institute of Biomedical Imaging and Bioengineering (R21EB029575); and UTHealth Innovation for Cancer Prevention Research Training Program Predoctoral Fellowship (CPRIT RP210042).

## Conflicts of Interest

The authors have no conflicts of interest to declare.

## References

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7. Yue X, Zhang XF, Yao Z, Lin S, Sun H. CliniQG4QA: Generating Diverse Questions for Domain Adaptation of Clinical Question Answering. ArXiv201016021 Cs. 2020 Nov 4.
8. Pampari A, Raghavan P, Liang J, Peng J. emrQA: A Large Corpus for Question Answering on Electronic Medical Records. In: EMNLP. Brussels, Belgium: Association for Computational Linguistics; 2018. p. 2357–68.
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