CVSim User Manual
 1 Introduction
The Cardiovascular Simulator, otherwise known as CVSim, is a hemodynamic simulation developed by the MIT Laboratory for Computational Physiology.
 2 Installation
 2.1 Supported Platforms
CVSim has been tested on the following platforms:
 • Windows XP
 • Mac OS X PPC
 • Mac OS X i386
 • Fedora Core 4
 • Fedora Core 5
 • Red Hat Enterprise Linux 4
CVSim is not supported on the following platforms:
 •  Solaris
 2.2 Installing Java Web Start
In order to run CVSim, you need to install Java Web Start. Java Web Start is part of the Java Runtime Engine (JRE). If you are using Windows or Linux, follow the instructions on the Sun website to install JRE 6. If you are using Linux, you need to perform an extra step and manually install the Java Plugin in your web browser. If you are using Mac OS X, run Software Update from the System Preferences. Install Java for Mac OS X 10.4, Release 5.
The first time you run CVSim, you will see a security warning that asks you, "The application’s digital signature cannot be verified. Do you want to run the application?". Click "Run". If you want to avoid that warning in the future, check the "Always trust content from this publisher" box. If you are using Internet Explorer, the security warning may be displayed behind your browser.
 2.3 Launching CVsim
Once Java Web Start has been installed on your system, one of the two links below can be used to start CVSim.

Launch CVSim []     Launch CVSim [alternate]

If you use a PhysioNet mirror, try the alternate link first; if it doesn't work, the first link can be used to launch CVSim from the master PhysioNet server.

 3 CVSim Window Components
The CVSim window is divided into four sections, a Simulation Parameters pane, a Graphics pane, a Strip Chart, and a Plot. There is also a toolbar with simulation controls.
The Simulation Controls toolbar allows the user to stop and start the simulation and turn the control systems on and off. The Simulation Parameters pane displays the simulation variables and outputs. The Graphics pane displays an anatomical and circuit representation of the simulation model. The strip chart allows the user to plot simulation outputs versus time. The strip chart behavior is based on an electrocardiogram (ECG) strip chart recorder. Like an ECG signal, the strip chart data scrolls from right to left. The plot allows the user to plot simulation outputs versus one another.
 4 Simulation Controls
The Simulation Controls toolbar contains the following components:
 • C:\Documents and Settings\Katie\My Documents\Work\cvsim\trunk\devel\java\classes\icons\go.gif Start the simulation
 • C:\Documents and Settings\Katie\My Documents\Work\cvsim\trunk\devel\java\classes\icons\stop.gif Stop the simulation
 • C:\Documents and Settings\Katie\My Documents\Work\cvsim\trunk\devel\java\classes\icons\ABgo.gif Turn on the arterial baroreflex control system
 • C:\Documents and Settings\Katie\My Documents\Work\cvsim\trunk\devel\java\classes\icons\ABstop.gif Turn off the arterial baroreflex control system
 • C:\Documents and Settings\Katie\My Documents\Work\cvsim\trunk\devel\java\classes\icons\CPgo.gif Turn on the cardiopulmonary reflex control system
 • C:\Documents and Settings\Katie\My Documents\Work\cvsim\trunk\devel\java\classes\icons\CPstop.gif Turn off the cardiopulmonary reflex control system
Watch the Simulation Controls Demo.
 5 Simulation Variables
Watch the Simulation Variables Demo.
 6 Graphics Pane
Watch the Graphics Pane Demo.
 7 Strip Chart and Plot
Watch the Strip Chart and Plot Demo.
 8 Simulating Patients (Coming Soon)