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Publications from the Research Resource for
Complex Physiologic Signals

This page lists recent publications by investigators affiliated with the Research Resource for Complex Physiologic Signals. The PhysioNet Publications page provides links to the full texts of some of these publications, and to other publications contributed to PhysioNet by non-affiliated investigators. Additional links to some of these publications can be found on pages maintained by Gari Clifford, Madalena Costa, Leon Glass, George Moody, and Gene Stanley.

The arrangement of these publications is by year, then alphabetically by author within each section.

1999 2000 2001 2002 2003 2004


1999 (July-December)

Al-Aweel IC, Krishnamurthy KB, Hausdorff JM, Mietus JE, Ives JR, Blum AS, Schomer DL, Goldberger AL. Postictal heart rate oscillations in partial epilepsy. Neurology 1999;53:1590-1592.

Amaral LAN, Ivanov PCh, Havlin S, Goldberger AL, Stanley HE. Multifractalidade do ritmo cardiaco. [feature article] Gazeta de Fisica 1999;22:4-9.

Hausdorff JM, Peng C-K, Wei JY, Goldberger AL. Fractal analysis of human walking rhythm. In: Winters JM, Crago PE, editors. Biomechanics and Neural Control of Movement. Springer-Verlag, 1999.

Havlin S, Amaral LAN, Ashkenazy Y, Goldberger AL, Ivanov PCh, Peng CK, Stanley HE. Application of statistical physics to heartbeat diagnosis. Physica A 1999; 274:99-110.

Ivanov PCh, Goldberger AL, Havlin S, Peng C-K, Rosenblum MG, Stanley HE. Wavelets in medicine and physiology. In: van den Berg JC, ed. Wavelets in Physics. Cambridge: Cambridge University Press, 1999.

Ivanov PCh, Bunde A, Amaral LAN, Havlin S, Fritsch-Yelle J, Baevsky RM, Stanley HE, Goldberger AL. Sleep-wake differences in scaling behavior of the human heartbeat: analysis of terrestrial and long-term space flight data. Europhys Lett 1999; 48:594-600.

Stanley HE, Amaral LAN, Goldberger AL, Havlin S, Ivanov PCh, Peng CK. Statistical physics in physiology: monofractal and multifractal approaches. Physica A 1999; 270:309-324.

Zong W, Moody GB, Mark RG. Reduction of false blood pressure alarms by use of electrocardiogram blood pressure relationships. Comput Cardiol 1999;26:305-308.


2000

Amaral LAN, Scala A, Barthelemy M, Stanley HE. Classes of small-world networks. Proc Natl Acad Sci USA 2000;97:11149-11152.

Ashkenazy Y, Ivanov PCh, Havlin S, Peng C-K, Yamamoto Y, Goldberger AL, Stanley HE. Volatility and sign correlations in heartbeat fluctuations. Comput Cardiol 2000;27:139-142.

Ashkenazy Y, Ivanov PCh, Havlin S, Peng C-K, Yamamoto Y, Goldberger AL, Stanley HE. Decomposition of heartbeat time series: Scaling analysis of the sign sequence. Comput Cardiol 2000;27:139-142.

Ballora M. Data analysis through auditory display: Applications in heart rate variability [Doctoral dissertation]. Montreal: McGill University, 2000.

Ballora M, Glass L, Pennycook B. Audification of heart rhythms in Csound. In: Belanger R, editor. The Csound Book: Perspectives in Software Synthesis, Sound Design, Signal Processing, and Programming. Cambridge, MA: MIT Press, 2000.

Ballora M, Pennycook B, Ivanov PCh, Goldberger AL, Glass L. Detection of obstructive sleep apnea through auditory display of heart rate variability. Comput Cardiol 2000;27:739-740.

Blum AS, Ives JR, Goldberger AL, Al-Aweel IC, Krishnamurthy KB, Drislane FW, Schomer DL. Oxygen desaturations triggered by partial seizures: Implications for cardiopulmonary instability in epilepsy. Epilepsia 2000;41:536-541.

Christini DJ, Hall K, Collins JJ, Glass L. Controlling cardiac arrhythmias: The relevance of nonlinear dynamics. In: Moss F, Gielen S, editors. Handbook of Biological Physics, Volume 4: Neuro-informatics, Neural Modelling. Amsterdam: Elsevier, 2000. pp. 205-227.

Glass L, Courtemanche M. Control of atrial fibrillation: A theoretical perspective. In: Ovsyscher IE, ed. Cardiac Arrhythmias and Device Therapy: Results and Perspectives for the New Century. Armonk, NY: Futura, 2000. pp. 87-94.

Goldberger AL, Amaral LAN, Glass L, Hausdorff JM, Ivanov PCh, Mark RG, Mietus JE, Moody GB, Peng C-K, Stanley HE. PhysioBank, PhysioToolkit, and PhysioNet: Components of a new Research Resource for Complex Physiologic Signals. Circulation 2000;101:e215-e220.

Gonzalez H, Nagai Y, Bub G, Glass L. Resetting and annihilating reentrant waves in a ring of cardiac tissue: Theory and experiment. In: Robnik M, Aizawa Y, Hasegawa H, Kuramoto Y, editors. “Let’s Face Chaos through Nonlinear Dynamics,” Proceedings of the 4th International Summer School/Conference, University of Maribor, June 27-July 11, 1999. Progress of Theoretical Physics Supplement 2000;139:83-89.

Gopikrishnan P, Plerou V, Liu Y-H, Amaral LAN, Gabaix X, Stanley HE. Scaling and correlation in financial time series. Physica 2000;287A:362-373.

Hausdorff JM, Lertratanakul A, Cudkowicz ME, Peterson AL, Kaliton D, Goldberger AL. Dynamic markers of altered gait rhythm in amyotrophic lateral sclerosis. J Appl Physiol 2000;88:2045-2053.

Heldt T, Shim EB, Kamm RD, Mark RG. Computational model of cardiovascular function during orthostatic stress. Comput Cardiol 2000;27:777-780.

Huikuri HV, Makikallio TH, Peng C-K, Goldberger AL, Hintze U, Moller M, for the DIAMOND Study Group. Fractal correlation properties of R-R interval dynamics and mortality in patients with depressed left ventricular function after an acute myocardial infarction. Circulation 2000;101:47-53.

Ivanov PCh, Amaral LAN, Goldberger AL, Havlin S, Rosenblum MG, Struzik Z, Stanley HE. Beyond 1/f: Multifractality in human heartbeat dynamics. In: Abbott D and Kish LB, editors. Unsolved problems of noise and fluctuations. UpoN’99: Second International Conference; 1999; Adelaide, Australia. New York: American Institute of Physics; 2000. p. 273-281.

Jager F, Taddei A, Emdin M, Antolic G, Dorn R, Moody GB, Smrdel A, Varanini M, Bordigiago S, Marchesi C, Mark RG. The long-term ST database: A research resource for algorithm development and physiologic studies of transient myocardial ischemia. Comput Cardiol 2000; 27:841-844.

McClennen S, Zimetbaum PJ, Ho KKL, Goldberger AL. Holter monitoring: Are two days better than one? Am J Cardiol 2000;86:562-564.

Mietus JE, Peng C-K, Ivanov PCh, Goldberger AL. Detection of obstructive sleep apnea from cardiac interbeat interval time series. Comput Cardiol 2000;27:753-756.

Moody GB, Mark RG, Goldberger AL, Penzel T. Stimulating rapid research advances via focused competition: The Computers in Cardiology Challenge 2000. Comput Cardiol 2000;27:207-210.

Moody GB, Mark RG, Goldberger AL. PhysioNet: A research resource for studies of complex physiologic and biomedical signals. Comput Cardiol 2000;27:179-182.

Nagai Y, Gonzalez H, Shrier A, Glass L. Paroxysmal starting and stopping of circulating waves in excitable media. Phys Rev Lett 2000;84:4248-4251.

Peng C-K, Hausdorff JM, Goldberger AL. Fractal mechanisms in neural control: human heartbeat and gait dynamics in health and disease. In: Walleczek J, editor. Nonlinear Dynamics, Self-Organization, and Biomedicine. Cambridge: Cambridge University Press, 2000. [Please note: this chapter is available as part of tutorial material on the PhysioNet website.]

Penzel T, Moody GB, Mark RG, Goldberger AL, Peter JH. The apnea-ECG database. Comput Cardiol 2000;27:255-258.

Plerou V, Gopikrishnan P, Rosenow B, Amaral LAN, Stanley HE. Econophysics: Financial time series from a statistical physics point of view. [J. L. Lebowitz Festschrift.] Physica 2000;279A:443-456.

Plerou V, Gopikrishnan P, Rosenow B, Amaral LAN, and Stanley HE. A random matrix theory approach to financial cross-correlations. [Conference on Economic Dynamics from the Physics Point of View, Bad Honnef, Germany.] Physica 2000;287A:374-382. Plerou V, Gopikrishnan P, Amaral LAN, Gabaix X, Stanley HE. Economic fluctuations and anomalous diffusion. Phys Rev E 2000;62:R3023-R3026.

Podobnik B, Ivanov PCh, Lee Y, Stanley HE. Systems with correlations in the variance: Generating power-law tails in probability distributions. Europhys Lett 2000;50:711-717.

Podobnik B, Ivanov PCh, Lee Y, Stanley HE. Scale-invariant truncated Lévy process. Europhys Lett 2000;52:491-497.

Saeed M, Mark RG. Multiparameter trend monitoring and intelligent displays using wavelet analysis. Computers in Cardiology 2000;27:797-800.

Schulte-Frohlinde V, Ashkenazy Y, Ivanov PCh, Glass L, Goldberger AL, Stanley HE. Stochastic elements in the study of pure parasystole. Comput Cardiol 2000;27:335-338.

Schulte-Frohlinde V, Ashkenazy Y, Ivanov PCh, Morley-Davies A, Glass L, Goldberger AL, Stanley HE. Finding hidden patterns in complex ventricular ectopy. Comput Cardiol 2000;27:335-338.

Shim EB, Kamm RD, Heldt T, Mark RG. Numerical analysis of blood flow through a stenosed artery using a coupled multiscale simulation method. Comput Cardiol 2000;27:219-222.

Stanley HE, Amaral LAN, Gopikrishnan P, Ivanov PCh, Keitt TH, Plerou V. Scale invariance and universality: Organizing principles in complex systems. International Conference on Statistical Physics, Taiwan. Physica A 2000;281:60-68.

Stanley HE, Gopikrishnan P, Plerou V, Amaral LAN. Quantifying fluctuations in economic systems by adapting methods of statistical physics. [Conference on Economic Dynamics from the Physics Point of View, Bad Honnef, Germany.] Physica 2000;287A:339-361.

Stanley HE, Amaral LAN, Goldberger AL, Havlin S, Ivanov PCh, Peng C-K. Monofractal and multifractal approaches to complex biomedical signals. In: Broomhead DS, Luchinskaya EA, McClintock PVE, Mullin T, editors. Stochastic and Chaotic Dynamics in the Lakes. Proceedings of the International “Stochaos” Workshop, Ambleside, Cumbria, United Kingdom. Melville, NY: American Institute of Physics Conference Proceedings 2000;502:133-145.

Stanley HE. Exotic statistical physics: Applications to biology, medicine, and economics. Karpacz International Conference on Exotic Statistical Physics. Physica A 2000;285:1-17.


2001

Amaral LAN, Ivanov PCh, Aoyagi N, Hidaka I, Tomono S, Goldberger AL, Stanley HE, Yamamoto Y. Behavioral-independent features of complex heartbeat dynamics. Phys Rev Lett 2001;86:6026-6029

Ashkenazy Y, Ivanov PCh, Havlin S, Peng CK, Goldberger AL, Stanley HE. Magnitude and sign correlations in heartbeat fluctuations. Phys Rev Lett 2001;86:1900-1903

Bernaola-Galvan P, Ivanov Pch, Amaral LAN, Stanley HE . Scale invariance in the nonstationarity of physiological signals. Phys Rev Lett 2001;87:168105

Choi HG, Mukkamala R, Moody GB, Mark RG. Do nonlinearities play a significant role in short term beat-to-beat variability? Comput Cardiol 2001;28:53-56

Glass L. Synchronization and rhythmic processes in physiology. Nature 2001;410:277-284.

Goldberger AL. Heartbeats, hormones, and health: Is variability the spice of life? Am J Respir Crit Care Med 2001;163:1289-1290.

Goldberger AL. Electrocardiography. In: Braunwald E, Fauci AS, Kasper DL, et al., editors. Harrison’s Principles of Internal Medicine, 15th edition. New York: McGraw-Hill, 2001.

Hausdorff JM, Nelson M, Kaliton D, Layne J, Bernstein M, Nuernberger A, Fiatarone Singh MA. The etiology and modification of gait instability in older adults: A randomized controlled trial of exercise. J Appl Physiol 2001;90:2117-2129.

Hausdorff JM, Rios D, Edelberg HK. Gait variability and fall risk in community-living older adults: A one-year prospective study. Arch Phys Med Rehabil 2001;82:1050-1056.

Hausdorff JM. Random walk analysis of gait: Fractal scaling and its changes with age and neurological disease. In: Proceedings of Frontiers in the Physics of Complex Systems, Dead Sea, Israel. April, 2001.

Hausdorff JM. Statistical physics and human walking: Random walk analysis and modeling of gait. In: Proceedings of Physics Fete 2001.

Hausdorff JM, Ashkenazy Y, Peng CK, Ivanov Pch, Stanley HE, Goldberger AL. When human walking becomes random walking: Fractal analysis and modeling of gait rhythm fluctuations. Physica A 2001;302:138-147

Henry IC, Moody GB, Mark RG, Goldberger AL. PhysioNet: an NIH Research Resource for physiologic datasets and open-source software. Proc14th IEEE CBMS Symposium 2001;14:245-250

Hu K, Chen Z, Ivanov PCh, Carpena P, Stanley. Effect of trends on detrended fluctuation analysis. Phys Rev E 2001;64(1):011114(19).

Ivanov PCh, Amaral LAN, Goldberger AL, Havlin S, Rosenblum MG, Stanley HE, Struzik Z. From 1/f noise to multifractal cascades in heartbeat dynamics. Chaos 2001;11:641-652.

Ivanov PCh, Goldberger AL, Stanley HE. Fractal and multifractal approaches in physiology. In: Bunde A, Kropp J, Schnellhuber J, editors. Science of Disaster: Market Crashes, Heart Attacks, and Climate Disruptions. Berlin: Springer Verlag, 2001.

Ivanov PCh, Podobnik B, Lee Y, Stanley HE. Truncated Levy process with scale-invariant behavior. Physica A 2001;299:154-160.

Ivanov PCh, Podobnik B, Lee Y, Chessa A, Stanley HE. Generating power-law tails in probability distributions. In: Garrido PL and Marro J, editors. Modeling Complex Systems: Sixth Granada Lectures on Computational Physics. American Institute of Physics, Melville, New York, 2001, p. 95-101.

Liljeros F, Edling CR, Amaral LAN, Stanley HE, Åberg Y. The web of human sexual contacts. Nature 2001;411:907-908.

Meck JV, Reyes CJ, Perez SA, Goldberger AL, Ziegler MG. Marked exacerbation of orthostatic intolerance after long- vs short-duration spaceflight in veteran astronauts. Psychosom Med 2001;63:865-873.

Mirvis DM, Goldberger AL. Electrocardiography. In: Braunwald E, Zipes DP, Libby P, editors. Heart Disease: A Textbook of Cardiovascular Medicine, 6th edition. Philadelphia: W.B. Saunders Company; 2001.

Moody GB, Mark RG. The MIT-BIH arrhythmia database. IEEE Eng Med Biol Mag 2001;20:45-50.

Moody GB, Mark RG, Goldberger AL. PhysioNet: A web-based resource for the study of physiologic signals. IEEE Eng Med Biol 2001;20:70-75.

Moody GB, Goldberger AL, McClennen S, Swiryn SP. Predicting the onset of atrial fibrillation: the Computers in Cardiology Challenge 2001. Comput Cardiol 2001;28:113-116

Mukkamala R, Cohen RJ. A forward model-based validation of cardiovascular system identification. Am J Physiol 2001;281:H2714-H2730

Mukkamala R, Mark RG, Cohen RJ. A noninvasive method for characterizing ventricular diastolic filling dynamics. IEEE-EMBS Conference 2001

Mukkamala R, Moody GB, Mark RG. Introduction of computational models to PhysioNet. Comput Cardiol 2001;28:77-80

Podobnik B, Matia K, Chessa A, Ivanov PCh, Lee Y, Stanley HE. Time evolution of stochastic processes with correlations in the variance: Stability in power-law tails of distributions. Physica A 2001;300:300-309

Saeed M, Mark RG. Efficient hemodynamic event detection utilizing relational databases and wavelet analysis. Comput Cardiol 2001;28:153-156

Schulte-Frohlinde V, Ashkenazy Y, Ivanov Pch, Glass L, Goldberger AL, Stanley HE. Noise effects on the complex patterns of abnormal heartbeats. Phys Rev Lett 2001;87:068104

Tateno K, Glass L. A method for detection of atrial fibrillation using RR intervals. Medical & Biological Engineering & Computing 2001;39:664-671.

Titcombe MS, Glass L, Guehl D, Beuter A. Dynamics of Parkinsonian tremor during deep brain stimulation. Chaos 2001;11:766-773

Zong W, Mukkamala R, Mark RG. A methodology for predicting paroxysmal atrial fibrillation based on ECG arrhythmia feature analysis. Comput Cardiol 2001;28:125-128


2002

Ashkenazy Y, Hausdorff JM, Ivanov PCh, Stanley HE. A stochastic model of human gait dynamics. Physica A 2002;316:662-670.

Baltadjieva R, Giladi N, Balash J, Herman T, Hausdorff JM. Gait changes in naive Parkinson’s disease patients. Proceedings of the Annual Meeting of the Israel Neurological Association. 2002.

Bastos de Figueiredo JC, Diambra L, Glass L, Malta CP. Chaos in two-looped negative feedback systems. Phys Rev E 2002;65:051905.

Bub G, Shrier A, Glass, L. Spiral wave generation in heterogeneous excitable media. Phys Rev Lett 2002;88;058101

Chen Z, Ivanov Pch, Hu K, Stanley HE. Effect of nonstationarities on detrended fluctuation analysis. Phys Rev E 2002;65:15

Christini D, Glass L. Mapping and control of complex cardiac arrhythmias. Chaos 2002;12:732-739.

Costa M, Goldberger AL, Peng CK. Multiscale entropy analysis of complex physiologic time series. Phys Rev Lett 2002;89:068102.

Giladi N, Schaafsma JD, Balash J, T Gurevich , Bartels A, Hausdorff JM. Clinical characterization of freezing of gait and its response to levodopa in Parkinson's disease. Proceedings of the Movement Disorder Society's 7th International Congress of Parkinson's Disease and Movement Disorders. 2002.

Giladi N, Herman T, Gurevich T, Rieder-Grossover I, Assaf, Y, Hausdorff JM. The non-specific gait disorder of the elderly: is it a disorder or a syndrome? Proceedings of the Movement Disorder Society's 7th International Congress of Parkinson's Disease and Movement Disorders. 2002.

Glass L, Nagai Y, Hall K, Talajic M, Nattel, S. Predicting the entrainment of reentrant cardiac waves using phase resetting curves. Phys Rev E 2002; 65:021908.

Glass L. Looking at dots. Mathematics Intelligencer 2002;24;37-43.

Glass L. Chaos in biological systems. In: Arbib MA, editor. The Handbook of Brain Theory and Neural Networks, 2nd Edition. Cambridge: MIT Press, 2002, pp. 205-208.

Goldberger AL. Chronic fatigue syndrome and hidden happenings of the heartbeat. Clin Auton Res 2002;12:228-230.

Goldberger AL, Peng CK, Lipsitz LA. What is physiologic complexity and how does it change with aging and disease? Neurobiol Aging 2002;23:23-26.

Goldberger AL, Amaral LAN, Hausdorff JM, Ivanov PCh, Peng CK, Stanley HE. Fractal dynamics in physiology: alterations with disease and aging. Proc Natl Acad Sci (USA) 2002;99[suppl 1]:2466-2472 (lead and cover article of issue). http://www.pnas.org/cgi/content/full/99/suppl_1/2466.

Hausdorff JM, Balash Y, Giladi N. Effects of a cognitive challenge on variability and fall risk in patients with Parkinson’s disease. To be presented at the national meeting of the American Geriatrics Society, May 2002

Hausdorff JM, Herman T, Gurevich T, Baltadjieva R, Giladi N. Is gait variability increased among older adults with high level gait disorders. Why? To be presented in the Presidential Poster Session at the national meeting of the American Geriatrics Society, May 2002

Hausdorff JM, Herman T, Gurevich T, Giladi N. Gait variability in older adults with high level gait disorders. Presented in the Presidential Poster Session at the national meeting of the American Geriatrics Society. J Am Geriatric Soc 2002;50:S159.

Hausdorff JM, Balash Y, Giladi N. Cognitive challenge increases gait variability and fall risk in patients with Parkinson’s disease. In: Proceedings of the National Meeting of the American Geriatrics Society. J Am Geriatric Soc 2002;50: S48.

Hausdorff JM, Schaafsma JD, Balash J, Bartels A, Gurevich T, Giladi N. Gait dynamics in subjects with freezing of gait and Parkinson’s disease: increased variability during usual walking. Proceedings of the Movement Disorder Society's 7th International Congress of Parkinson's Disease and Movement Disorders. 2002.

Hausdorff JM, Balash J, Giladi N. Cognitive challenge increases gait variability in patients with Parkinson's disease. Proceedings of the Movement Disorder Society's 7th International Congress of Parkinson's Disease and Movement Disorders. 2002.

Hausdorff JM, Schaafsma JD, Balash J, Bartels A, Gurevich T, Giladi N. Impaired rhythmicity during usual walking in subjects with Parkinson’s disease and freezing of gait. In Proceedings of the Annual Meeting of the Israel Neurological Association. 2002.

Herman T, Gurevich T, Baltadjieva R, Giladi N, Hausdorff JM. Gait variability & fractal dynamics of older adults with high level gait disturbances. Proceedings of the Movement Disorder Society's 7th International Congress of Parkinson's Disease and Movement Disorders. 2002.

Ivanov PCh, Goldberger AL, Stanley HE. Fractal and multifractal approaches in physiology. In: Bunde A, Kropp J and Schellnhuber HJ, editors. The science of disaster: climate disruptions, heart attacks, and market crashes. Berlin: Springer Verlag; 2002. p.458.

Ivanov PCh, Bernaola-Galvan P, Amaral LAN, Stanley HE. Fractal features in the nonstationarity of physiological time series. In: Novak MM, editor. Emergent Nature. Singapore: World Scientific; 2002. p.55-65. [Proceedings of the 7th International Multidisciplinary Conference on Complexity and Fractals in Nature; 2002 Mar 17-20; Granada, Spain.]

Ivanov PCh, Lo CC. Stochastic approaches to modeling of physiological rhythms in modeling bio-medical signals. In: editors Nardulli G and Stramaglia S, editors. Modeling Biomedical Signals. Singapore: World Scientific Publishing Co; 2002. pp. 28-50.

Jorgensen P, Schafer C, Guerra PG, Talajic M, Nattel S, Glass L. A mathematical model of human atrioventricular nodal function incorporating concealed conduction. Bull Math Biol 2002;64:1083-1099.

Kantelhardt JW, Ashkenazy Y, Ivanov PCh, Bunde A, Havlin S, Penzel T, Peter JH, Stanley HE. Characterization of sleep stages by correlations of heartbeat increments. Phys Rev E 2002;65:051908(6)

Kantelhardt JW, Zschiegner SA, Koscielny-Bunde E, Havlin S, Bunde A, Stanley HE. Multifractal detrended fluctuation analysis of nonstationary times series. Physica A 2002;316:87-114.

Karasik R, Sapir N, Ashkenazy Y, Ivanov PCh, Dvir I, Lavie P, Havlin S. Correlation differences in heartbeat fluctuations during rest and exercise. Phys Rev E 2002;66:062902.

Keitt TH, Amaral LAN, Buldyrev SV, Stanley HE. Scaling in the growth of geographically subdivided populations: invariant patterns from a continent-wide biological survey. Philos Trans R Soc Lond B Biol Sci. 2002;357:627-33.

Lo CC, Amaral LAN, Havlin S, Ivanov PCh, Peng CK, Peter JH, Penzel T, Stanley HE. Scale-free dynamics of awakenings during healthy human sleep. Europhys Lett 2002;57:625-631

Matia K, Amaral LAN, Stanley HE. Non-Levy behavior of price fluctuations in commodity markets. Phys Rev E 2002;66:045103.

Mietus JE, Peng CK, Henry I, Goldsmith RL, Goldberger AL. The pNNx-files: reexamining a widely-used heart rate variability measure. Heart 2002;88:378-380

Mossa S, Barthelemy M, Stanley HE, Amaral LAN. Truncation of power law behavior in scale-free network models due to information filtering. Phys Rev Lett 2002;88:138701.

Mukkamala R, Cohen RJ, and Mark RG. A computational model-based validation of Guyton's analysis of cardiac output and venous return curves. Comput Cardiol 2002; 29: 561-564.

Peng CK, Mietus, JE, Liu Y, Lee C, Hausdorff JM, Stanley HE, Goldberger AL, Lipsitz LA. Quantifying fractal dynamics of human respiration: age and gender effects. Ann Biomed Eng 2002;30:683-692.

Plerou V, Gopikrishnan P, Rosenow B, Amaral LAN, Guhr T, Stanley HE. A random matrix approach to cross-correlations in financial data. Phys Rev E 2002;65:066126.

Saeed M, Lieu C, Raber G, Mark RG. MIMIC II: A massive temporal ICU patient database to support research in intelligent patient monitoring. Comput Cardiol 2002;29:641-644.

Schulte-Frohlinde V, Ashkenazy Y, Goldberger AL, Ivanov PCh, Costa M, Morley-Davies A, Stanley HE, Glass L. Complex patterns of abnormal heartbeats. Phys Rev E 2002;66:031901(12).

Sheridan P, Solomont J, Hausdorff JM. Divided attention increases gait variability in Alzheimer’s Disease. Presented in the Presidential Poster Session at the national meeting of the American Geriatrics Society. J Am Geriatric Soc 2002;50:S167.

Shim EB, Youn CH, Heldt T, Kamm RD, Mark RG. Computational modeling of the cardiovascular system after Fontan procedure. In: editors Colosimo A, Giuliani A, P. Sirabella Lecture Notes in Computer Science 2526. Berlin: Springer-Verlag, 2002, pp. 105-114.

Stanley HE, Amaral LAN, Buldyrev SV, Gopikrishnan P, Plerou V, Salinger MA. Self-organized complexity in economic systems. Proc Natl Acad Sci (USA) 2002;99[suppl 1]:2561-2565.

Zong W, Wang P, Leung B, Moody GB, Mark RG. An automated, web-enabled and searchable database system for archiving electrogram and related data from implantable cardioverter defibrillators. Comput Cardiol 2002;29:269-272.

Zong W, Wang P, Leung B, Moody GB, Garan AR, Mark RG. A new web-enabled searchable archiving system for ICD stored data and waveforms. Circulation 2002;106(suppl II):II-408.


2003

Ashkenazy Y, Havlin S, Ivanov PCh, Peng CK, Schulte-Frohlinde V, Stanley HE. Magnitude and sign scaling in power-law correlated time series. Physica A 2003;323:19.

Bartels A, Balash Y. Gurevich T, Schaafsma JD, Hausdorff JM, Giladi N. Relationship between freezing of gait (FOG) and other features of Parkinson’s: FOG is not correlated with bradykinesia. J Clin Neurosci 2003;10:584-588.

Belair J, Glass L. Introduction to dynamics in nonlinear difference and differential equations. In: Beuter A, Glass L, Mackey MC, Titcombe MS, editors. Nonlinear Dynamics in Physiology and Medicine. New York: Springer-Verlag; 2003.

Beuter A, Glass L, Mackey MC, Titcombe MS, editors. Nonlinear Dynamics in Physiology and Medicine. New York: Springer-Verlag; 2003.

Bub G, Tateno K, Shrier A, Glass L. Spontaneous initiation and termination of complex rhythms in cardiac cell culture. J Cardiovasc Electrophysiol 2003;14(10):229-236.

Chen JJS, Heldt T, Verghese GC, Mark RG. Analytical solution to simplified circulatory model using piecewise linear elastance. Comp Cardiol 2003;30.

Chen Z, Ivanov PCh, Hu K, Stanley HE, Novak V. Synchronization patterns in cerebral blood flow and peripheral blood pressure under minor stroke. In: Schimansky-Geier L, Abbott D, Neiman A, Van den Broeck C, editors. Noise in complex systems and stochastic dynamics. SPIE Proceedings, 5114, p.498-506 (2003).

Costa M, Peng CK, Goldberger AL, Hausdorff JM. Multiscale entropy analysis of human gait dynamics. Physica A, 2003;330(1):53-60.

Costa M, Moody GB, Henry I, Goldberger AL. PhysioNet: an NIH research resource for complex signals. J Electrocardiol 2003;36Suppl:139-44.

Costa M, Goldberger AL, Peng CK. Comment: Intermittently decreased beat-to-beat variability in congestive heart failure. Phys Rev Lett 2003;91:119802.

Costa M, Healey JA. Multiscale entropy analysis of complex heart rate dynamics: discrimination of age and heart failure effects. Comp Cardiol 2003;30.

Frankel S, Giladi N, Gruendlinger L, Baltadjieva R, Herman T, Hausdorff JM. Treadmill walking as an "external cue" to improve gait rhythm and stability in Parkinson’s disease. Proceedings of the Israel Neurological Association, December 2003.

Fukuda K, Amaral LAN, Stanley HE. Similarities between communication dynamics in the Internet and the autonomic nervous system. Europhys Lett 2003;62:189-195.

Gavrila A, Peng CK, Chan JL, Mietus JE, Goldberger AL, Mantzoros CS. Diurnal and ultradian dynamics of serum adiponectin in healthy men: comparison with leptin, circulating soluble leptin receptor and cortisol patterns. J Clin Ednocrinol Metab 2003;88:2838-43. (Dr. Gavrila, a fellow in endocrinology, received a 2003 Henry Christian Award from the American Federation of Medical Research for this work.)

Giladi N, Herman T, Gurevich T, Rieder-Grossover I, Assaf, Y, Hausdorff JM. Clinical characteristics of patients with idiopathic senile gait disorder: evidence for a multi-system neurodegenerative syndrome. In Proceedings of the American Geriatrics Society, May, 2003.

Giladi N, Herman T, Hausdorff JM. Falls and fear of falling. In: Proceedings of the Eleventh International Conference of the International Psychogeriatric Association, Chicago, 2003.

Giladi N, Herman T, Rieder-Grossover I, Assaf, Y, Gurevich T, Hausdorff JM. High level gait disorder: is it primary neurodenerative or vascular in origin? Proceedings of the International Congress on Vascular Dementia, Prague, Czech Republic, October, 2003.

Giladi N, Mordechovitch M, Hausdorff JM, Shabtai H, Balash Y, Gruendlinger L, Borenstein N. Screening for falls, stroke or dementia risk factors in a self- referral, middle age population: is it worth the effort? Proceedings of the Israel Neurological Association, December 2003.

Giladi N, Sheridan PL, Hausdorff JM. The interrelationships between gait and cognitive function. In: Hanin I, A Fisher A, R Cacabelos R, editors. Progress in AD / PD. London: Martin Dunitz Inc. 2003; in press.

Glass L. Resetting and entraining biological rhythms. In: Beuter A, Glass L, Mackey MC, Titcombe MS, editors. Nonlinear Dynamics in Physiology and Medicine. New York: Springer-Verlag; 2003.

Gozolchiany A, Moshel S, Hausdorff JM, Simon ES, Havlin S. Decaying of phase synchronization - a physiological tool. In Proceedings of the 49th meeting of the Israel Physics Society, Ramat Gan, Israel, December, 2003.

Gonzalez H, Nagai Y, Bub G, Glass L, Shrier A. Reentrant waves in a ring of embryonic chick ventricular cells imaged with a Ca2+ sensitive dye. BioSystems 2003;71:71-80.

Hausdorff JM, Balash Y, Giladi N. Effects of cognitive challenge on gait variability in patients with Parkinson’s disease. J Geriatr Psych Neurol 2003;16:53-58.

Hausdorff JM, Schaafsm J, Balash Y, Bartels AL, Gurevich T, N Giladi. Impaired regulation of stride variability in Parkinson’s disease subjects with freezing of gait. Exp Brain Res 2003;142:187-194.

Hausdorff JM, Herman T, Baltadjieva R, Gurevich T, Giladi N. Balance and gait in older adults with systemic hypertension. Am J Cardiol 2003;91:643-645.

Hausdorff JM, Balash J, Giladi N. Time series analysis of leg movements during freezing of gait in Parkinson’s disease: akinesia, rhyme or reason? Physica A 2003;321:565-570.

Hausdorff JM, Herman T, Baltadjieva R, Giladi N. Altered balance and gait in elderly hypertensives: association between fractal index of gait and blood pressure. Proceedings of International Society for Posture and Gait Research, 2003.

Heldt T, Oefinger MB, Hoshiyama M, Mark RG. Circulatory response to passive and active changes in posture. Comp Cardiol 2003;30.

Herman T, Hausdorff JM, Giladi N. Gait disturbances in older adults. Neurology Update 2003;11:4-8.

Herman T, Hausdorff JM, Giladi N. Gait disturbances in the elderly. Int Med Rev 2003;48:21-26.

Hu K, Ivanov PCh, Chen Z, Hilton MF, Stanley HE, Shea SA. Novel multiscale regulation in human motor activity, in fluctuations and noise. In: Bezrukov SM, Frauenfelder H, Moss F, editors. Biological, biophysical, and biomedical systems. SPIE Proceedings, 5110, p.235-243 (2003).

Ivanov PCh, Ashkenazy Y, Kantelhardt JW, Stanley HE. Quantifying heartbeat dynamics by magnitude and sign correlations. UPoN 2003;665:383-391.

Ivanov PCh. Long-range dependence in heartbeat dynamics. In: Rangarajan G, Ding M, editors. Processes with long-range correlations: theory and applications, Springer lecture notes in physics 621. New York: Springer Verlag;2003. p. 339-368.

Ivanova K, Ackerman TP, Clothiaux EE, Ivanov PCh, Stanley HE, Ausloos M. Time correlations and 1/f behavior in backscattering radar reflectivity measurements from cirrus cloud ice fluctuations. J Geophys Res 2003;108(D9): 4268.

Jager F, Taddei A, Moody GB, Emdin M, Antolic G, Dorn R, Smrdel A, Marchesi C, Mark RG. Long-term ST database: a reference for the development and evaluation of automated ischaemia detectors and for the study of the dynamics of myocardial ischaemia. Med Biol Eng Comput 2003;41:172-182.

Kantelhardt JW, Havlin S, Ivanov PCh. Modeling transient correlations in heartbeat dynamics during sleep. Europhys Lett 2003;62:147-153.

Kappler K, Edwards R, Glass L. Dynamics in high dimensional model gene networks. Signal Processing 2003;83:789-798.

Lowenthal J, Gruendlinger L, Baltadjieva R, Herman T, Hausdorff JM, Nir Giladi N. Effects of rhythmic auditory stimulation on gait dynamics in Parkinson's disease. Proceedings of the Israel Neurological Association, December 2003.

McClennen S, Nathanson LA, Safran C, Goldberger AL. ECG Wave-Maven: an Internet-based electrocardiography self-assessment program for students and clinicians. Med Educ Online 2003;8:2. (http://www.med-ed-online.org/issue2.htm#v8)

Moody GB, Dakin M, Mark RG. Web-enabled physiologic signal processing and analysis. Proc. World Congress on Medical Physics and Biomedical Engineering. Sydney 2003.

Moody GB, Jager F. Distinguishing ischemic from non-ischemic ST changes: the Physionet/Computers in Cardiology Challenge 2003. Comp Cardiol 2003;30.

Mukkamala R, Reisner AT, Hojman HM, Mark RG, Cohen RJ. Continuous cardiac output monitoring by peripheral blood pressure waveform analysis. Comp Cardiol 2003;30.

Pinto DS, Ho KK, Zimetbaum PJ, Pedan A, Goldberger AL. Sinus versus nonsinus tachycardia in the emergency department: Importance of age and heart rate. BMC Cardiovasc Disord 2003;3:7.

Sapir N, Karasik R, Havlin S, Simon E, Hausdorff JM. Detecting scaling in the period dynamics of multimode signals: Application to Parkinsonian tremor. Phys Rev E 2003;67:031903.

Schaafsma JD,Giladi N, Balash Y, Bartels AL Gurevich T, Hausdorff JM. Gait dynamics in Parkinson's disease: relationship to parkinsonian features, falls and response to Levodopa. J Neurol Sci 2003;212:47-53.

Schaafsma JD, Balash Y, Gurevich T, Bartels AL, Hausdorff JM, Giladi N. Characterization of freezing of gait subtypes and the response of each to levodopa in Parkinson’s disease. Eur J Neurol 2003;10:391-398.

Sheridan P, Solomont J, Kowall N, Hausdorff JM. Influence of executive function on locomotor function: divided attention increases gait variability in Alzheimer’s disease. J Am Geriatr Soc 2003;51:1633-1637.

Suki B, Alencar AM, Frey U, Ivanov PCh, Buldyrev SV, Majumdar A, Stanley HE, Dawson CA, Krenz GS, Mishima M. Fluctuations, noise and scaling in the cardio-pulmonary system. Fluct Noise Lett 2003;3:R1-R25.

Yang CC, Hseu SS, Yien HW, Goldberger AL, Peng CK. Linguistic analysis of the human heartbeat using frequency and rank order statistics. Phys Rev Lett 2003;90:108103.

Yang CC, Peng CK, Yien HW, Goldberger AL. Information categorization approach to literary authorship disputes. Physica A 2003;329:473-483.

Zong W, Heldt T, Moody GB. An open-source algorithm to detect onset of arterial blood pressure pulses. Comp Cardiol 2003;30.

Zong W, Moody GB, Jiang D. A robust open-source algorithm to detect onset and duration of QRS complexes. Comp Cardiol 2003;30.


2004

Ballora M, Pennycook B, Ivanov PCh, Goldberger AL, Glass L. Heart rate sonification: A new approach to medical diagnosis. Leonardo 2004;37:41-46.

Bloem, BR. Hausdorff JM, Visser J, Giladi N. Falls and freezing of gait in Parkinson’s disease: a review of two interconnected, episodic phenomena. Mov Disorders 2004; in press.

Carbone A, Castelli G, Stanley HE. Analysis of clusters formed by the moving average of a long-rangecorrelated time series. Phys Rev E 2004;69:026105.

Costa M, Goldberger AL, Peng CK. Comment: Multiscale entropy analysis of complex physiologic time series. Phys Rev Lett 2004;92:089804.

Frenkel-Toledo S, Giladi N, Gruendlinger L, Baltadjieva R, Hausdorff JM. Treadmill walking as an external cue to improve gait rhythm and stability in Parkinson's disease. To Appear In: Proceedings of the National Meeting of the American Geriatrics Society, Las Vegas, May, 2004.

Giladi N, Hausdorff JM, Balash Y. Episodic and continuous gait disturbances in Parkinson’s disease. In: N Galvez-Jiminez N, editor. The Scientific Basis for the Treatment of Parkinson’s disease. 2nd edition (in press).

Glass L. Simple mathematical models for complicated biological systems. In: Klonowski, E, editor. Euroattractor 2002. PABST Science Publisher. 2004; in press.

Glass L. Cardiac arrhythmias and the electrocardiogram. In: Scott A, editor. Encyclopedia of Nonlinear Science. New York: Routledge, 2004; in press.

Glass L. Cardiac oscillations and arrhythmia analysis. Deisboeck T, Kepler T, Kresh Y, editors. Complex Systems Science in Biomedicine. New York: Kluwer, 2004; in press.

Gurevich T, Groozman GB, Giladi N, Drory VA, Hausdorff JM, Korczyn AD. R-R interval variation in Parkinson’s disease and multiple system atrophy. Acta Neurol Scand 2004;109:276.

Hausdorff JM, Herman T, Gurevich T, Giladi N. Gait instability and fractal dynamics of older adults with a "cautious" gait. Why do certain older adults walk fearfully? Gait & Posture 2004; in press.

Hausdorff JM. Stride variability: beyond length and frequency. Gait & Posture 2004; in press.

Hausdorff JM, Mordechovitch M, Giladi N. Gait variability in older adults with age-associated cognitive decline. To Appear In: Proceedings of the National Meeting of the American Geriatrics Society, Las Vegas, May, 2004.

Hu K, Ivanov PCh, Chen Z, Hilton MF, Stanley HE, Shea SA. Non-random fluctuations and multi-scale dynamics regulation of human activity. Physica A 2004 Jun;337(1-2):307-318.

Jager F, Moody GB, Mark RG. Protocol to assess robustness of ST analysers: a case study. Physiological Measurement 2004 Jun;25(3)629-643.

Peng CK, Henry IC, Mietus JE, Hausdorff JM, Khalsa G, Benson H, Ary L. Goldberger AL. Heart rate dynamics during three forms of meditation. Int J Cardiol 2004 May;95(1)19-27.

Springer S, Giladi N, Simon E, Hausdorff JM. Deficits in executive function in idiopathic elderly fallers: association with fall risk. To Appear In: Proceedings of the National Meeting of the American Geriatrics Society, Las Vegas, May, 2004.

Yang CC, Hseu SS, Yien HW, Goldberger AL, Peng CK. Reply to Kraskov A et al. comment on linguistic analysis of the human heartbeat using frequency and rank order statistics. Phys Rev Lett 2004;92:LGK921.

Yeh GY, Wood MJ, Lorell BH, Stevenson LW, Goldberger AL, Wayne PM, Eisenberg DM, Davis RB, Phillip RS. Effect of Tai Chi mind-body movement therapy on functional status and exercise capacity in patients with chronic heart failure: a randomized controlled trial. Am J Med 2004;in press.

Yogev G, Giladi N, Gruendlinger L, Baltadjieva R, Simon E, Hausdorff JM. Executive function, mental loading and gait variability in Parkinson's disease. To Appear In: Proceedings of the National Meeting of the American Geriatrics Society, Las Vegas, May, 2004.

Zong W, Moody GB, Mark RG. Reduction of false arterial blood pressure alarms using signal quality assessment and electrocardiogram-arterial blood pressure relationships. Med Biol Eng Comput 2004; in press.
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