The Long-Term ST Database
The Long-Term ST Database contains 86 lengthy ECG
recordings of 80
human subjects, chosen to exhibit a variety of events of ST segment
changes, including ischemic ST episodes, axis-related non-ischemic ST
episodes, episodes of slow ST level drift, and episodes containing
mixtures of these phenomena. The database was created to support
development and evaluation of algorithms capable of accurate
differentiation of ischemic and non-ischemic ST events, as well as
basic research into mechanisms and dynamics of myocardial ischemia.
Half (43) of these 86 recordings, representing
42 of the 80 subjects, were contributed to PhysioNet by the
creators of the database in February 2003, and the remaining half of the
database was contributed in May 2007. (A corrected version of s30801.dat
was also posted together with the second half of the database.) Detailed clinical notes and ST deviation
trend plots are provided for all 86 records. The entire Long-Term ST
Database is also available from its original home page at the
Laboratory for
Biomedical Computer Systems and Imaging at the University of Ljubljana,
Slovenia
The individual recordings of the Long-Term ST Database are between 21
and 24 hours in duration, and contain two or three ECG signals. Each
ECG signal has been digitized at 250 samples per second with 12-bit
resolution over a range of ±10 millivolts. Each record
includes a set of meticulously verified ST episode and signal quality
annotations, together with additional beat-by-beat QRS annotations and
ST level measurements.
For each recording, the first digit in the record name (2 or 3) indicates
the number of ECG signals. Records obtained from the same subject have
names that differ in the last digit only.
Each record is represented by 12 files, all with the same base name (the record
name) and a suffix that identifies the file type:
- a (text) .hea (header) file, containing detailed clinical
information for the subject;
- a (binary) .dat (signal) file, containing the digitized
ECG signals;
- several (binary) annotation files, identifiable by suffix:
- .ari (automatically-generated beat annotations)
- .atr (manually corrected beat annotations)
- .16a (automatically-generated, manually-corrected ST-segment
measurements, based on 16-second moving averages,
updated for each beat)
- .sta (ST-segment episode annotations, Vmin = 75 µV,
Tmin = 30 s; see below)
- .stb (ST-segment episode annotations, Vmin = 100 µV,
Tmin = 30 s)
- .stc (ST-segment episode annotations, Vmin = 100 µV,
Tmin = 60 s)
- a (text) .cnt file, containing counts of ST episodes in the
.sta, .stb, and .stc files
- a (text) .stf file, containing the ST level function,
the linearly approximated baseline ST level function (ST level reference
function), and the ST deviation function for each ECG lead;
- a (binary) .tsr.zip file, containing additional data files
needed by SEMIA (see below):
- a (text) _fin.dmy file, containing fine diagnostic and
morphology time series
- a (text) _raw.dmy file, containing raw diagnostic and
morphology time series
- a (text) _1.sta file, containing ST segment markers
(Before using SEMIA, download and unzip the .tsr.zip file
for the record(s) of interest into your current directory.)
- a (binary) .klt.zip file, which decompresses to a (text)
.klt file, containing
- time series of ST segment Karhunen-Loève transform
coefficients (ST segment principal components)
- time series of QRS complex Karhunen-Loève transform
coefficients (QRS complex principal components)
The measurements in the .16a files were used to construct ST level and
deviation functions for each signal, as recorded in the .stf files.
(Further details about the .stf, tsr.zip, and
.klt.zip files are available here.) ST
episodes were identified independently for each signal, based on its ST
deviation function and on these criteria:
- An episode begins when the magnitude of the ST deviation function
first exceeds 50 µV;
- The deviation must reach a magnitude of Vmin or more throughout a
continuous interval of at least Tmin;
- The episode ends when the deviation becomes smaller than 50 µV,
provided that it does not exceed 50 µV in the following 30 seconds.
Since differing criteria may be appropriate depending on the application,
three sets of ST episode annotations are provided. The annotation codes
used in the .sta, .stb, .stc, and .16a
files are described here.
For each record, the numbers of ST episodes as determined by each of the three
sets of criteria are summarized in an additional text file (with suffix
.cnt). The deviation functions and the locations of the episodes are
presented graphically in a set of trend plots here. Each
record is represented by a 24-hour plot (_00-24.png) and by five
6-hour plots which overlap by one hour (_00-06.png,
05-11.png, etc.).
Development of the Long-Term ST Database was an inter-institutional and
international effort coordinated by Prof. Franc Jager of the Faculty of
Computer and Information Science, University of Ljubljana, Ljubljana, Slovenia.
Other investigators include: Roman Dorn, PhD, and Ales Smrdel, MSc, of the
Faculty of Computer and Information Science, Ljubljana; Dr. Gorazd Antolic of
the University Medical Center, Ljubljana, Slovenia; Drs. Alessandro Taddei and
Michele Emdin of the CNR Institute for Clinical Physiology (the creators of the
European ST-T Database European ST-T Database), Pisa, and
Prof. Carlo Marchesi of the University of Firenze, Firenze, Italy; and
Dr. Roger Mark and George Moody of the Massachusetts Institute of Technology
(the creators of the MIT-BIH Arrhythmia Database),
Cambridge, MA, USA, and the Beth Israel Deaconess Medical Center, Boston, MA,
USA. The project was supported by Medtronic, Inc. (Minneapolis, MN, USA) and
Zymed, Inc. (Camarillo, CA, USA). Development of the Long-Term ST Database
began in 1995 and was completed in 2002. We thank all who contributed to this
project; further details are here.
Several sources contributed recordings to the Long-Term ST Database:
-
Eleven of the recordings included in the Long-Term ST Database are from the
initial Long-Term ST Database developed under a joint U.S.-Slovenian research
project between 1995 and 1998.
-
Ten additional recordings of the Long-Term ST Database are from the collection
originally gathered by the Pisa group for the European ST-T Database, which
contains two-hour excerpts of some of these same recordings. The original
analog recordings were redigitized for the Long-Term ST Database; since the
signals have been rescaled as a result, direct comparison of the annotations in
the European ST-T Database records with those for the corresponding portions of
the Long-Term ST Database records is not possible. The inclusion of these
recordings in the Long-Term ST Database allows study of the dynamics of
ischemic ST changes over a much longer period in these previously well-studied
subjects. Among the samples available here, record s20021 includes the two-hour
segment that was previously digitized to produce record e0113 of the European
ST-T Database.
-
Another 18 of the LTSTDB recordings, those containing recordings with three ECG
signals, were contributed to the project by Zymed, Inc.
The annotation of the Long-Term ST Database was performed using SEMIA, a program written by the group
in Ljubljana for this purpose. SEMIA provides an interactive
graphical user interface to a semi-automated algorithm for measurement
of ST levels. Sources for SEMIA, and a precompiled version for GNU/Linux,
are available here (as individual files), and as
a gzip-compressed tar archive.
Each recording was reviewed independently by expert annotators using
SEMIA at each of the three sites (Ljubljana, Pisa, and Cambridge).
Participants met several times annually to obtain the consensus
reference annotations.
A series of SEMIA screenshots illustrates the annotation process. (Use your
browser's Back button to return to this page after following the links to these
screenshots in the next paragraph. If you have problems viewing the
screenshots in your browser, please read this
note.)
The first task faced by the expert annotators was to mark the locations of the
PQ junction (the isoelectric level) and the J point, based on 16-second
averaged cardiac cycles chosen at frequent intervals throughout the recordings.
These marks serve as guideposts for the automated ST level measurement
algorithm that performs the next step. The experts then examine the time
series of ST level measurements in order to locate and to mark a set of local reference points
(marked as LR in the upper panel of the figure). These are used to construct a
piecewise linear baseline ST level function, which may vary over time as a
result of body position changes or other factors unrelated to ischemia,
especially in subjects with prior myocardial infarctions. Axis shifts reflect body
position changes, and are usually most apparent in the QRS complexes (note the
changes in the QRS principal components, KL1 - KL5, in the lower panel of the
figure). By contrast, when ischemic ST changes occur, they are most apparent
in the principal components of the ST segment (see the lower panel in this screenshot).
Local references are placed before and after each such episode, and the
episodes are annotated next. During this process, the expert annotators have
the option of viewing either the ST level time
series or the ST deviation time
series (formed by subtracting the baseline ST level function from the
uncorrected ST level time series), as shown in the upper panels of the two
screenshots. For further details, see reference 4 below.
Software for producing printed
documentation of the Long-Term ST Database is available for Linux or Unix.
The software produces compact trend plots of the ST level and ST deviation
time series, with indicators of ischemic and non-ischemic ST episodes.
For further information, please contact:
Franc Jager
Laboratory of Biomedical Computer Systems and Imaging
University of Ljubljana
Faculty of Computer and Information Science
Trzaska 25
1000 Ljubljana, Slovenia
E-mail: franc.jager@fri.uni-lj.si
Alessandro Taddei
National Research Council (CNR)
Institute of Clinical Physiology
Via Moruzzi 1
56124 Pisa, Italy
E-mail: taddei@ifc.cnr.it
George B. Moody
Harvard-MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology, Room E25-505A
77 Massachusetts Avenue
Cambridge, MA 02139 USA
E-mail: george@mit.edu
References
- Franc Jager, George B. Moody, Alessandro Taddei, Gorazd Antolic,
Mitja Zabukovec, Maja Skrjanc, Michele Emdin, and Roger G. Mark.
Development of a Long-Term Database for Assessing the Performance
of Transient Ischemia Detectors.
Computers in Cardiology 1996, pp. 481-484,
IEEE Press. ISSN 0276-6547.
[HTML]
[LaTeX]
[PostScript]
[PDF]
- Franc Jager, George B. Moody, Alessandro Taddei, Gorazd Antolic,
Ales Smrdel, Boris Glavic, Michele Emdin, Carlo Marchesi, and
Roger G. Mark.
Research Resources for Development and Evaluation of Transient
Ischemia Detectors.
Proc. Computer-Aided Data Analysis in Medicine (CADAM 98),
Informatica Medica Slovenica, 5(1,2):45-54, 1998.
ISSN 1318-2129.
- Franc Jager, George B. Moody, Alessandro Taddei, Gorazd Antolic,
Michele Emdin, Ales Smrdel, Boris Glavic, Carlo Marchesi, and
Roger G. Mark.
A Long-Term ST Database for Development and Evaluation of Ischemia
Detectors.
Computers in Cardiology 1998, pp. 301-304,
IEEE Press. ISSN 0276-6547.
- Franc Jager, Alessandro Taddei, Michele Emdin, Gorazd Antolic,
Roman Dorn, George B. Moody, Boris Glavic, Ales Smrdel, M Varanini,
Mitja Zabukovec, Simone Bordigiago, Carlo Marchesi, and
Roger G. Mark.
The Long-Term ST Database: A Research Resource for Algorithm
Development and Physiologic Studies of Transient Myocardial Ischemia.
Computers in Cardiology 2000, pp. 841-844.
[HTML]
[LaTeX]
[PostScript]
[PDF]
- Franc Jager, Alessandro Taddei, George B. Moody, Michele Emdin,
Gorazd Antolic, Roman Dorn, Ales Smrdel, Carlo Marchesi, and
Roger G. Mark.
Long-term ST database: a reference for the development and evaluation
of automated ischaemia detectors and for the study of the dynamics of
myocardial ischaemia.
Medical & Biological Engineering & Computing
41(2):172-183 (2003).
[HTML]
[PDF]
Name Last modified Size Description
![[DIR]](/icons/back.gif)
Parent Directory -
![[TXT]](/icons/text.gif)
00README 20-May-2002 16:00 2.8K file format info
![[ ]](/icons/index.gif)
ANNOTATORS 09-May-2008 11:49 357 list of annotators
![[ ]](/icons/unknown.gif)
MD5SUMS 18-Jun-2007 13:35 40K
RECORDS 18-Jun-2007 13:17 602 list of record names
RECORDS-2003 28-Feb-2003 10:53 301 list of record names
SHA1SUMS 18-Jun-2007 13:39 47K
SHA256SUMS 18-Sep-2007 12:39 79K
![[DIR]](/icons/folder.gif)
figures/ 17-Sep-2001 04:48 - SEMIA screenshots
lt00/ 09-Feb-2001 01:17 - CinC 2000 paper
lt03/ 14-Apr-2003 21:58 -
lt96/ 09-Feb-2001 01:16 - CinC 1996 paper
notes/ 09-Dec-2003 11:22 - clinical notes
s20011.16a 20-May-2002 16:00 11M ST segment measurements
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s20011.ari 20-May-2002 16:00 359K automatically-generate>
s20011.atr 20-May-2002 16:00 207K reference annotations
s20011.cnt 20-May-2002 16:00 4.2K ST episode counts
s20011.dat 20-May-2002 16:00 59M digitized signal(s)
s20011.hea 20-May-2002 16:00 1.7K header file
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s20011.klt.zip 20-May-2002 16:00 543K ST and QRS KL coeffici>
s20011.sta 20-May-2002 16:00 4.2K ST episode annotations
s20011.stb 20-May-2002 16:00 3.2K ST episode annotations
s20011.stc 20-May-2002 16:00 3.2K ST episode annotations
s20011.stf 20-May-2002 16:00 2.6M ST level/deviation fun>
s20011.tsr.zip 26-Mar-2002 03:28 4.0M SEMIA data files
s20021.16a 20-May-2002 16:00 9.1M ST segment measurements
s20021.ari 20-May-2002 16:00 174K automatically-generate>
s20021.atr 20-May-2002 16:00 200K reference annotations
s20021.cnt 20-May-2002 16:00 4.3K ST episode counts
s20021.dat 20-May-2002 16:00 54M digitized signal(s)
s20021.hea 20-May-2002 16:00 1.4K header file
s20021.klt.zip 20-May-2002 16:00 574K ST and QRS KL coeffici>
s20021.sta 20-May-2002 16:00 11K ST episode annotations
s20021.stb 20-May-2002 16:00 11K ST episode annotations
s20021.stc 20-May-2002 16:00 9.4K ST episode annotations
s20021.stf 20-May-2002 16:00 2.4M ST level/deviation fun>
s20021.tsr.zip 20-May-2002 16:00 3.7M SEMIA data files
s20031.16a 20-May-2002 16:00 11M ST segment measurements
s20031.ari 20-May-2002 16:00 214K automatically-generate>
s20031.atr 20-May-2002 16:00 229K reference annotations
s20031.cnt 20-May-2002 16:00 4.3K ST episode counts
s20031.dat 20-May-2002 16:00 61M digitized signal(s)
s20031.hea 05-Apr-2008 18:05 1.7K header file
s20031.hea- 20-May-2002 16:00 1.6K header file
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s20031.sta 20-May-2002 16:00 2.8K ST episode annotations
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s20031.stc 20-May-2002 16:00 2.3K ST episode annotations
s20031.stf 20-May-2002 16:00 2.7M ST level/deviation fun>
s20031.tsr.zip 26-Mar-2002 03:31 3.9M SEMIA data files
s20041.16a 20-May-2002 16:00 9.4M ST segment measurements
s20041.ari 20-May-2002 16:00 213K automatically-generate>
s20041.atr 20-May-2002 16:00 246K reference annotations
s20041.cnt 20-May-2002 16:00 4.3K ST episode counts
s20041.dat 20-May-2002 16:00 62M digitized signal(s)
s20041.hea 05-Apr-2008 18:05 2.3K header file
s20041.hea- 20-May-2002 16:00 2.3K header file
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s20041.sta 20-May-2002 16:00 7.2K ST episode annotations
s20041.stb 20-May-2002 16:00 6.3K ST episode annotations
s20041.stc 20-May-2002 16:00 5.8K ST episode annotations
s20041.stf 20-May-2002 16:00 2.7M ST level/deviation fun>
s20041.tsr.zip 20-May-2002 16:00 3.7M SEMIA data files
s20051.16a 06-Jan-1970 19:42 12M ST segment measurements
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s20051.atr 06-Jan-1970 19:43 276K reference annotations
s20051.cnt 06-Jan-1970 19:43 4.3K ST episode counts
s20051.dat 06-Jan-1970 19:43 55M digitized signal(s)
s20051.hea 06-Jan-1970 19:47 1.5K header file
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s20051.sta 06-Jan-1970 19:47 5.0K ST episode annotations
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s20051.stf 28-Jan-1970 20:37 2.4M ST level/deviation fun>
s20051.tsr.zip 28-Jan-1970 20:37 4.4M SEMIA data files
s20061.16a 20-May-2002 16:00 12M ST segment measurements
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s20061.atr 20-May-2002 16:00 294K reference annotations
s20061.cnt 20-May-2002 16:00 4.3K ST episode counts
s20061.dat 20-May-2002 16:00 59M digitized signal(s)
s20061.hea 20-May-2002 16:00 1.1K header file
s20061.klt.zip 20-May-2002 16:00 491K ST and QRS KL coeffici>
s20061.sta 20-May-2002 16:00 4.1K ST episode annotations
s20061.stb 20-May-2002 16:00 3.1K ST episode annotations
s20061.stc 20-May-2002 16:00 2.8K ST episode annotations
s20061.stf 20-May-2002 16:00 2.6M ST level/deviation fun>
s20061.tsr.zip 20-May-2002 16:00 4.2M SEMIA data files
s20071.16a 06-Jan-1970 19:52 9.1M ST segment measurements
s20071.ari 06-Jan-1970 19:53 310K automatically-generate>
s20071.atr 06-Jan-1970 19:53 167K reference annotations
s20071.cnt 06-Jan-1970 19:53 4.2K ST episode counts
s20071.dat 06-Jan-1970 19:53 54M digitized signal(s)
s20071.hea 06-Jan-1970 19:57 1.1K header file
s20071.klt.zip 28-Jan-1970 20:38 453K ST and QRS KL coeffici>
s20071.sta 06-Jan-1970 19:57 3.4K ST episode annotations
s20071.stb 06-Jan-1970 19:57 3.0K ST episode annotations
s20071.stc 06-Jan-1970 19:57 2.7K ST episode annotations
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s20071.tsr.zip 28-Jan-1970 20:38 3.3M SEMIA data files
s20081.16a 20-May-2002 16:00 12M ST segment measurements
s20081.ari 20-May-2002 16:00 433K automatically-generate>
s20081.atr 20-May-2002 16:00 244K reference annotations
s20081.cnt 20-May-2002 16:00 4.3K ST episode counts
s20081.dat 20-May-2002 16:00 59M digitized signal(s)
s20081.hea 20-May-2002 16:00 1.5K header file
s20081.klt.zip 20-May-2002 16:00 590K ST and QRS KL coeffici>
s20081.sta 20-May-2002 16:00 8.0K ST episode annotations
s20081.stb 20-May-2002 16:00 5.5K ST episode annotations
s20081.stc 20-May-2002 16:00 5.0K ST episode annotations
s20081.stf 20-May-2002 16:00 2.6M ST level/deviation fun>
s20081.tsr.zip 20-May-2002 16:00 4.4M SEMIA data files
s20091.16a 06-Jan-1970 20:02 12M ST segment measurements
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s20091.atr 06-Jan-1970 20:03 223K reference annotations
s20091.cnt 06-Jan-1970 20:03 4.2K ST episode counts
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s20091.sta 06-Jan-1970 20:07 3.9K ST episode annotations
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s20091.tsr.zip 28-Jan-1970 20:39 4.3M SEMIA data files
s20101.16a 20-May-2002 16:00 6.0M ST segment measurements
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s20101.atr 20-May-2002 16:00 192K reference annotations
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s20101.sta 20-May-2002 16:00 2.0K ST episode annotations
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s20101.tsr.zip 20-May-2002 16:00 2.5M SEMIA data files
s20111.16a 06-Jan-1970 20:11 8.9M ST segment measurements
s20111.ari 06-Jan-1970 20:11 467K automatically-generate>
s20111.atr 06-Jan-1970 20:11 212K reference annotations
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s20111.sta 06-Jan-1970 20:15 8.6K ST episode annotations
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s20111.tsr.zip 28-Jan-1970 20:40 3.6M SEMIA data files
s20121.16a 20-May-2002 16:00 7.2M ST segment measurements
s20121.ari 20-May-2002 16:00 319K automatically-generate>
s20121.atr 20-May-2002 16:00 170K reference annotations
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s20121.sta 20-May-2002 16:00 6.6K ST episode annotations
s20121.stb 20-May-2002 16:00 6.3K ST episode annotations
s20121.stc 20-May-2002 16:00 6.2K ST episode annotations
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s20121.tsr.zip 20-May-2002 16:00 2.6M SEMIA data files
s20131.16a 06-Jan-1970 20:19 8.9M ST segment measurements
s20131.ari 06-Jan-1970 20:20 397K automatically-generate>
s20131.atr 06-Jan-1970 20:20 290K reference annotations
s20131.cnt 06-Jan-1970 20:20 4.3K ST episode counts
s20131.dat 06-Jan-1970 20:20 54M digitized signal(s)
s20131.hea 06-Jan-1970 20:24 1.9K header file
s20131.klt.zip 28-Jan-1970 20:41 545K ST and QRS KL coeffici>
s20131.sta 06-Jan-1970 20:24 4.9K ST episode annotations
s20131.stb 06-Jan-1970 20:24 4.1K ST episode annotations
s20131.stc 06-Jan-1970 20:24 3.9K ST episode annotations
s20131.stf 28-Jan-1970 20:41 2.4M ST level/deviation fun>
s20131.tsr.zip 28-Jan-1970 20:41 3.3M SEMIA data files
s20141.16a 20-May-2002 16:00 13M ST segment measurements
s20141.ari 20-May-2002 16:00 426K automatically-generate>
s20141.atr 20-May-2002 16:00 233K reference annotations
s20141.cnt 20-May-2002 16:00 4.2K ST episode counts
s20141.dat 20-May-2002 16:00 56M digitized signal(s)
s20141.hea 20-May-2002 16:00 1.3K header file
s20141.klt.zip 20-May-2002 16:00 556K ST and QRS KL coeffici>
s20141.sta 20-May-2002 16:00 11K ST episode annotations
s20141.stb 20-May-2002 16:00 8.4K ST episode annotations
s20141.stc 20-May-2002 16:00 6.2K ST episode annotations
s20141.stf 20-May-2002 16:00 2.5M ST level/deviation fun>
s20141.tsr.zip 20-May-2002 16:00 4.6M SEMIA data files
s20151.16a 06-Jan-1970 20:28 7.4M ST segment measurements
s20151.ari 06-Jan-1970 20:29 156K automatically-generate>
s20151.atr 06-Jan-1970 20:29 173K reference annotations
s20151.cnt 06-Jan-1970 20:29 4.3K ST episode counts
s20151.dat 06-Jan-1970 20:29 61M digitized signal(s)
s20151.hea 06-Jan-1970 20:33 1.7K header file
s20151.klt.zip 28-Jan-1970 20:41 632K ST and QRS KL coeffici>
s20151.sta 06-Jan-1970 20:33 7.2K ST episode annotations
s20151.stb 06-Jan-1970 20:33 5.7K ST episode annotations
s20151.stc 06-Jan-1970 20:33 5.2K ST episode annotations
s20151.stf 28-Jan-1970 20:42 2.7M ST level/deviation fun>
s20151.tsr.zip 28-Jan-1970 20:42 3.4M SEMIA data files
s20161.16a 20-May-2002 16:00 8.9M ST segment measurements
s20161.ari 20-May-2002 16:00 164K automatically-generate>
s20161.atr 20-May-2002 16:00 234K reference annotations
s20161.cnt 20-May-2002 16:00 4.3K ST episode counts
s20161.dat 20-May-2002 16:00 61M digitized signal(s)
s20161.hea 20-May-2002 16:00 1.8K header file
s20161.klt.zip 20-May-2002 16:00 693K ST and QRS KL coeffici>
s20161.sta 20-May-2002 16:00 11K ST episode annotations
s20161.stb 20-May-2002 16:00 9.5K ST episode annotations
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s20451.tsr.zip 28-Jan-1970 20:58 3.3M SEMIA data files
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