Gait Dynamics in Neuro-Degenerative Disease Data Base

Neuro-degenerative disease often affects gait and mobility. To understand better the pathophysiology of these diseases and to improve our ability to measure responses to therapeutic interventions, it may be helpful to quantify gait dynamics accurately. The records in this database are from patients with Parkinson's disease (n = 15), Huntington's disease (n = 20), or amyotrophic lateral sclerosis (n = 13). Records from 16 healthy control subjects are also included here.

The raw data were obtained using force-sensitive resistors, with the output roughly proportional to the force under the foot. Stride-to-stride measures of footfall contact times were derived from these signals, as illustrated below. (Click here for a PostScript version of this figure.)

[Examples of Gait Time Series]

Each of the 64 records is identified by the name of the subject group (hunt, park, als, or control) followed by an arbitrary ID number. The four files associated with each record have names beginning with the record name, and suffixes indicating the type and contents of the file:

SuffixContents
.hea Header (text)
.letLeft foot signal (binary)
.ritRight foot signal (binary)
.tsDerived time series (text)

Within the time series (.ts) files, the contents are:

ColumnContents
1Elapsed Time (sec)
2Left Stride Interval (sec)
3Right Stride Interval (sec)
4Left Swing Interval (sec)
5Right Swing Interval (sec)
6Left Swing Interval (% of stride)
7Right Swing Interval (% of stride)
8Left Stance Interval (sec)
9Right Stance Interval (sec)
10Left Stance Interval (% of stride)
11Right Stance Interval (% of stride)
12Double Support Interval (sec)
13Double Support Interval (% of stride)

Please note that these time series have not been filtered.

A separate file (subject-description.txt, a tab-delimited text file) includes clinical information for each subject, including age, gender, height, weight, walking speed, and a measure of disease severity or duration. For the subjects with Parkinson's disease, this is the Hohn and Yahr score (a higher score indicates more advanced disease). For the subjects with Huntington's disease, this is the total functional capacity measure (a lower score indicates more advanced functional impairment). For the subjects with amyotrophic lateral sclerosis, the number here is the time in months since the diagnosis of the disease. For the control subjects, an arbitrary 0 is used as a place holder.

Questions for study

We have done some initial analyses of these data sets. Much, however, is still unknown. For example: Are the dynamics of the sub-phases of the stride (e.g., stance and swing) identical to that of the stride itself? What is the effect of disease on gait asymmetry? Are stride dynamics nonlinear? Does this change with disease?

References

We have reported the association between disease and the dynamics of the stride time. For more information about our analyses of these data files, please see:

Address for correspondence: jhausdor@caregroup.harvard.edu

Icon  Name                    Last modified      Size  Description
[PARENTDIR] Parent Directory - [   ] DOI 2015-09-21 13:00 19 [   ] als8.hea- 2000-11-07 12:52 53 header file [   ] als1.hea- 2000-11-07 12:52 56 header file [   ] als2.hea- 2000-11-07 12:52 56 header file [   ] als3.hea- 2000-11-07 12:52 56 header file [   ] als4.hea- 2000-11-07 12:52 56 header file [   ] als5.hea- 2000-11-07 12:52 56 header file [   ] als6.hea- 2004-05-24 21:56 56 header file [   ] als7.hea- 2000-11-07 12:52 56 header file [   ] als9.hea- 2000-11-07 12:52 56 header file [   ] hunt1.hea- 2000-11-07 12:54 56 header file [   ] hunt2.hea- 2000-11-07 12:54 56 header file [   ] hunt3.hea- 2000-11-07 12:54 56 header file [   ] hunt4.hea- 2000-11-07 12:54 56 header file [   ] hunt6.hea- 2000-11-07 12:54 56 header file [   ] hunt7.hea- 2000-11-07 12:54 56 header file [   ] park4.hea- 2000-11-07 12:55 56 header file [   ] park5.hea- 2000-11-07 12:55 56 header file [   ] park6.hea- 2000-11-07 12:55 56 header file [   ] park8.hea- 2000-11-07 12:56 56 header file [   ] park9.hea- 2000-11-07 12:56 56 header file [   ] hunt9.hea- 2000-11-07 12:54 57 header file [   ] park1.hea- 2000-11-07 12:55 57 header file [   ] park2.hea- 2000-11-07 12:55 57 header file [   ] park3.hea- 2000-11-07 12:55 57 header file [   ] als10.hea- 2000-11-07 12:52 59 header file [   ] als11.hea- 2000-11-07 12:52 59 header file [   ] als12.hea- 2000-11-07 12:52 59 header file [   ] als13.hea- 2000-11-07 12:52 59 header file [   ] hunt12.hea- 2000-11-07 12:55 59 header file [   ] hunt15.hea- 2000-11-07 12:55 59 header file [   ] hunt16.hea- 2000-11-07 12:55 59 header file [   ] hunt17.hea- 2000-11-07 12:55 59 header file [   ] hunt18.hea- 2000-11-07 12:55 59 header file [   ] hunt19.hea- 2000-11-07 12:55 59 header file [   ] hunt20.hea- 2000-11-07 12:55 59 header file [   ] hunt5.hea- 2000-11-07 12:54 59 header file [   ] hunt8.hea- 2000-11-07 12:54 59 header file [   ] park10.hea- 2000-11-07 12:56 59 header file [   ] park12.hea- 2000-11-07 12:56 59 header file [   ] park13.hea- 2000-11-07 12:56 59 header file [   ] park14.hea- 2000-11-07 12:56 59 header file [   ] park7.hea- 2000-11-07 12:56 59 header file [   ] hunt10.hea- 2000-11-07 12:54 60 header file [   ] hunt11.hea- 2000-11-07 12:54 60 header file [   ] hunt13.hea- 2000-11-07 12:55 60 header file [   ] hunt14.hea- 2000-11-07 12:55 60 header file [   ] park11.hea- 2000-11-07 12:56 62 header file [   ] park15.hea- 2000-11-07 12:56 62 header file [   ] control6.hea- 2000-11-07 12:53 66 header file [   ] control8.hea- 2000-11-07 12:53 66 header file [   ] control1.hea- 2000-11-07 12:53 68 header file [   ] control10.hea- 2000-11-07 12:53 68 header file [   ] control11.hea- 2000-11-07 12:53 68 header file [   ] control12.hea- 2000-11-07 12:53 68 header file [   ] control13.hea- 2000-11-07 12:53 68 header file [   ] control15.hea- 2000-11-07 12:54 68 header file [   ] control2.hea- 2000-11-07 12:53 68 header file [   ] control3.hea- 2000-11-07 12:53 68 header file [   ] control4.hea- 2000-11-07 12:53 68 header file [   ] control5.hea- 2000-11-07 12:53 68 header file [   ] control7.hea- 2008-03-02 09:31 68 header file [   ] control9.hea- 2000-11-07 12:53 68 header file [   ] control14.hea- 2000-11-07 12:54 71 header file [   ] control16.hea- 2000-11-07 12:54 71 header file [   ] als2.hea 2012-11-17 15:04 111 header file [   ] als4.hea 2012-11-17 15:04 111 header file [   ] als6.hea 2012-11-17 15:04 112 header file [   ] hunt3.hea 2012-11-17 15:06 112 header file [   ] als5.hea 2012-11-17 15:04 113 header file [   ] hunt7.hea 2012-11-17 15:06 113 header file [   ] park7.hea 2012-11-17 15:06 113 header file [   ] als3.hea 2012-11-17 15:04 114 header file [   ] als9.hea 2012-11-17 15:04 114 header file [   ] als1.hea 2012-11-17 15:04 115 header file [   ] als11.hea 2012-11-17 15:04 115 header file [   ] als8.hea 2012-11-17 15:04 115 header file [   ] hunt1.hea 2012-11-17 15:04 115 header file [   ] hunt9.hea 2012-11-17 15:06 115 header file [   ] park1.hea 2012-11-17 15:06 115 header file [   ] park2.hea 2012-11-17 15:06 115 header file [   ] park4.hea 2012-11-17 15:06 115 header file [   ] park5.hea 2012-11-17 15:06 115 header file [   ] park6.hea 2012-11-17 15:06 115 header file [   ] als10.hea 2012-11-17 15:04 116 header file [   ] als7.hea 2012-11-17 15:04 116 header file [   ] hunt2.hea 2012-11-17 15:06 116 header file [   ] hunt6.hea 2012-11-17 15:06 116 header file [   ] park3.hea 2012-11-17 15:06 116 header file [   ] park9.hea 2012-11-17 15:06 116 header file [   ] als13.hea 2012-11-17 15:04 117 header file [   ] hunt15.hea 2012-11-17 15:04 117 header file [   ] hunt5.hea 2012-11-17 15:06 117 header file [   ] hunt8.hea 2012-11-17 15:06 117 header file [   ] park11.hea 2012-11-17 15:06 117 header file [   ] park15.hea 2012-11-17 15:06 117 header file [   ] hunt11.hea 2012-11-17 15:04 118 header file [   ] hunt14.hea 2012-11-17 15:04 118 header file [   ] hunt17.hea 2012-11-17 15:05 118 header file [   ] hunt18.hea 2012-11-17 15:06 118 header file [   ] hunt19.hea 2012-11-17 15:06 118 header file [   ] park12.hea 2012-11-17 15:06 118 header file [   ] park14.hea 2012-11-17 15:06 118 header file [   ] park8.hea 2012-11-17 15:06 118 header file [   ] als12.hea 2012-11-17 15:04 119 header file [   ] hunt10.hea 2012-11-17 15:04 119 header file [   ] hunt16.hea 2012-11-17 15:04 119 header file [   ] hunt20.hea 2012-11-17 15:06 119 header file [   ] hunt4.hea 2012-11-17 15:06 119 header file [   ] park10.hea 2012-11-17 15:06 119 header file [   ] park13.hea 2012-11-17 15:06 119 header file [   ] hunt12.hea 2012-11-17 15:04 120 header file [   ] control8.hea 2012-11-17 15:04 122 header file [   ] hunt13.hea 2012-11-17 15:04 122 header file [   ] control6.hea 2012-11-17 15:04 123 header file [   ] control9.hea 2012-11-17 15:04 123 header file [   ] control10.hea 2012-11-17 15:04 124 header file [   ] control13.hea 2012-11-17 15:04 124 header file [   ] control5.hea 2012-11-17 15:04 124 header file [   ] control7.hea 2012-11-17 15:04 124 header file [   ] control1.hea 2012-11-17 15:04 125 header file [   ] control16.hea 2012-11-17 15:04 125 header file [   ] control2.hea 2012-11-17 15:04 126 header file [   ] control12.hea 2012-11-17 15:04 127 header file [   ] control14.hea 2012-11-17 15:04 127 header file [   ] control3.hea 2012-11-17 15:04 127 header file [   ] control11.hea 2012-11-17 15:04 128 header file [   ] control4.hea 2012-11-17 15:04 128 header file [   ] control15.hea 2012-11-17 15:04 129 header file [   ] RECORDS 2000-12-21 10:52 447 list of record names [TXT] subject-description.txt 2000-11-07 12:08 2.3K clinical information [TXT] TEST.shtml 2016-09-23 15:44 9.5K [TXT] als12.ts 2000-11-07 12:52 10K time series [TXT] als4.ts 2000-11-07 12:52 12K time series [TXT] als7.ts 2000-11-07 12:52 14K time series [   ] MD5SUMS 2012-11-17 15:24 14K [TXT] hunt13.ts 2000-11-07 12:55 14K time series [TXT] als6.ts 2000-11-07 12:52 15K time series [TXT] als13.ts 2000-11-07 12:52 16K time series [TXT] hunt16.ts 2000-11-07 12:55 16K time series [TXT] als1.ts 2000-11-07 12:52 17K time series [   ] SHA1SUMS 2012-11-17 15:24 17K [TXT] control15.ts 2000-11-07 12:54 17K time series [TXT] park8.ts 2000-11-07 12:56 17K time series [TXT] als5.ts 2000-11-07 12:52 18K time series [TXT] als9.ts 2000-11-07 12:52 18K time series [TXT] als3.ts 2000-11-07 12:52 18K time series [TXT] hunt15.ts 2000-11-07 12:55 19K time series [TXT] hunt10.ts 2000-11-07 12:54 19K time series [TXT] park4.ts 2000-11-07 12:55 19K time series [TXT] park9.ts 2000-11-07 12:56 19K time series [TXT] hunt2.ts 2000-11-07 12:54 19K time series [TXT] park7.ts 2000-11-07 12:56 19K time series [TXT] als11.ts 2000-11-07 12:52 20K time series [TXT] park11.ts 2000-11-07 12:56 20K time series [TXT] park3.ts 2000-11-07 12:55 20K time series [TXT] hunt3.ts 2000-11-07 12:54 20K time series [TXT] als8.ts 2000-11-07 12:52 20K time series [TXT] hunt7.ts 2000-11-07 12:54 20K time series [TXT] park15.ts 2000-11-07 12:56 20K time series [TXT] hunt11.ts 2000-11-07 12:54 20K time series [TXT] control2.ts 2000-11-07 12:53 21K time series [TXT] als2.ts 2000-11-07 12:52 21K time series [TXT] hunt19.ts 2000-11-07 12:55 21K time series [TXT] control12.ts 2000-11-07 12:53 21K time series [TXT] park1.ts 2000-11-07 12:55 21K time series [TXT] als10.ts 2000-11-07 12:52 21K time series [TXT] hunt20.ts 2000-11-07 12:55 21K time series [TXT] park12.ts 2000-11-07 12:56 21K time series [TXT] hunt17.ts 2000-11-07 12:55 21K time series [TXT] control14.ts 2000-11-07 12:54 21K time series [TXT] control16.ts 2000-11-07 12:54 21K time series [TXT] control5.ts 2000-11-07 12:53 21K time series [TXT] park13.ts 2000-11-07 12:56 21K time series [TXT] control13.ts 2000-11-07 12:53 22K time series [TXT] hunt18.ts 2000-11-07 12:55 22K time series [TXT] hunt14.ts 2000-11-07 12:55 22K time series [TXT] control3.ts 2000-11-07 12:53 22K time series [TXT] hunt8.ts 2000-11-07 12:54 22K time series [TXT] hunt12.ts 2000-11-07 12:55 22K time series [TXT] control1.ts 2000-11-07 12:53 22K time series [TXT] control7.ts 2000-11-07 12:53 22K time series [TXT] control8.ts 2000-11-07 12:53 22K time series [TXT] hunt6.ts 2000-11-07 12:54 23K time series [TXT] hunt5.ts 2000-11-07 12:54 23K time series [TXT] park5.ts 2000-11-07 12:55 23K time series [TXT] control4.ts 2000-11-07 12:53 23K time series [TXT] hunt4.ts 2000-11-07 12:54 23K time series [TXT] control11.ts 2000-11-07 12:53 23K time series [TXT] park6.ts 2000-11-07 12:55 23K time series [TXT] control6.ts 2000-11-07 12:53 23K time series [TXT] hunt9.ts 2000-11-07 12:54 23K time series [TXT] control9.ts 2000-11-07 12:53 24K time series [TXT] control10.ts 2000-11-07 12:53 24K time series [TXT] park2.ts 2000-11-07 12:55 24K time series [TXT] park14.ts 2000-11-07 12:56 24K time series [   ] SHA256SUMS 2012-11-17 15:24 24K [TXT] park10.ts 2000-11-07 12:56 25K time series [TXT] hunt1.ts 2000-11-07 12:54 27K time series [IMG] example-ts.png 2000-12-21 11:39 32K [   ] example-ts.ps 2000-11-07 12:13 33K [   ] als1.let 2012-11-17 15:04 132K left foot signal [   ] als1.rit 2012-11-17 15:04 132K right foot signal [   ] als10.let 2012-11-17 15:04 132K left foot signal [   ] als10.rit 2012-11-17 15:04 132K right foot signal [   ] als11.let 2012-11-17 15:04 132K left foot signal [   ] als11.rit 2012-11-17 15:04 132K right foot signal [   ] als12.let 2012-11-17 15:04 132K left foot signal [   ] als12.rit 2012-11-17 15:04 132K right foot signal [   ] als13.let 2012-11-17 15:04 132K left foot signal [   ] als13.rit 2012-11-17 15:04 132K right foot signal [   ] als2.let 2012-11-17 15:04 132K left foot signal [   ] als2.rit 2012-11-17 15:04 132K right foot signal [   ] als3.let 2012-11-17 15:04 132K left foot signal [   ] als3.rit 2012-11-17 15:04 132K right foot signal [   ] als4.let 2012-11-17 15:04 132K left foot signal [   ] als4.rit 2012-11-17 15:04 132K right foot signal [   ] als5.let 2012-11-17 15:04 132K left foot signal [   ] als5.rit 2012-11-17 15:04 132K right foot signal [   ] als6.let 2012-11-17 15:04 132K left foot signal [   ] als6.rit 2012-11-17 15:04 132K right foot signal [   ] als7.let 2012-11-17 15:04 132K left foot signal [   ] als7.rit 2012-11-17 15:04 132K right foot signal [   ] als8.let 2012-11-17 15:04 132K left foot signal [   ] als8.rit 2012-11-17 15:04 132K right foot signal [   ] als9.let 2012-11-17 15:04 132K left foot signal [   ] als9.rit 2012-11-17 15:04 132K right foot signal [   ] control1.let 2012-11-17 15:04 132K left foot signal [   ] control1.rit 2012-11-17 15:04 132K right foot signal [   ] control10.let 2012-11-17 15:04 132K left foot signal [   ] control10.rit 2012-11-17 15:04 132K right foot signal [   ] control11.let 2012-11-17 15:04 132K left foot signal [   ] control11.rit 2012-11-17 15:04 132K right foot signal [   ] control12.let 2012-11-17 15:04 132K left foot signal [   ] control12.rit 2012-11-17 15:04 132K right foot signal [   ] control13.let 2012-11-17 15:04 132K left foot signal [   ] control13.rit 2012-11-17 15:04 132K right foot signal [   ] control14.let 2012-11-17 15:04 132K left foot signal [   ] control14.rit 2012-11-17 15:04 132K right foot signal [   ] control15.let 2012-11-17 15:04 132K left foot signal [   ] control15.rit 2012-11-17 15:04 132K right foot signal [   ] control16.let 2012-11-17 15:04 132K left foot signal [   ] control16.rit 2012-11-17 15:04 132K right foot signal [   ] control2.let 2012-11-17 15:04 132K left foot signal [   ] control2.rit 2012-11-17 15:04 132K right foot signal [   ] control3.let 2012-11-17 15:04 132K left foot signal [   ] control3.rit 2012-11-17 15:04 132K right foot signal [   ] control4.let 2012-11-17 15:04 132K left foot signal [   ] control4.rit 2012-11-17 15:04 132K right foot signal [   ] control5.let 2012-11-17 15:04 132K left foot signal [   ] control5.rit 2012-11-17 15:04 132K right foot signal [   ] control6.let 2012-11-17 15:04 132K left foot signal [   ] control6.rit 2012-11-17 15:04 132K right foot signal [   ] control7.let 2012-11-17 15:04 132K left foot signal [   ] control7.rit 2012-11-17 15:04 132K right foot signal [   ] control8.let 2012-11-17 15:04 132K left foot signal [   ] control8.rit 2012-11-17 15:04 132K right foot signal [   ] control9.let 2012-11-17 15:04 132K left foot signal [   ] control9.rit 2012-11-17 15:04 132K right foot signal [   ] hunt1.let 2012-11-17 15:04 132K left foot signal [   ] hunt1.rit 2012-11-17 15:04 132K right foot signal [   ] hunt10.let 2012-11-17 15:04 132K left foot signal [   ] hunt10.rit 2012-11-17 15:04 132K right foot signal [   ] hunt11.let 2012-11-17 15:04 132K left foot signal [   ] hunt11.rit 2012-11-17 15:04 132K right foot signal [   ] hunt12.let 2012-11-17 15:04 132K left foot signal [   ] hunt12.rit 2012-11-17 15:04 132K right foot signal [   ] hunt13.let 2012-11-17 15:04 132K left foot signal [   ] hunt13.rit 2012-11-17 15:04 132K right foot signal [   ] hunt14.let 2012-11-17 15:04 132K left foot signal [   ] hunt14.rit 2012-11-17 15:04 132K right foot signal [   ] hunt15.let 2012-11-17 15:04 132K left foot signal [   ] hunt15.rit 2012-11-17 15:04 132K right foot signal [   ] hunt16.let 2012-11-17 15:04 132K left foot signal [   ] hunt16.rit 2012-11-17 15:04 132K right foot signal [   ] hunt17.let 2012-11-17 15:05 132K left foot signal [   ] hunt17.rit 2012-11-17 15:05 132K right foot signal [   ] hunt18.let 2012-11-17 15:06 132K left foot signal [   ] hunt18.rit 2012-11-17 15:06 132K right foot signal [   ] hunt19.let 2012-11-17 15:06 132K left foot signal [   ] hunt19.rit 2012-11-17 15:06 132K right foot signal [   ] hunt2.let 2012-11-17 15:06 132K left foot signal [   ] hunt2.rit 2012-11-17 15:06 132K right foot signal [   ] hunt20.let 2012-11-17 15:06 132K left foot signal [   ] hunt20.rit 2012-11-17 15:06 132K right foot signal [   ] hunt3.let 2012-11-17 15:06 132K left foot signal [   ] hunt3.rit 2012-11-17 15:06 132K right foot signal [   ] hunt4.let 2012-11-17 15:06 132K left foot signal [   ] hunt4.rit 2012-11-17 15:06 132K right foot signal [   ] hunt5.let 2012-11-17 15:06 132K left foot signal [   ] hunt5.rit 2012-11-17 15:06 132K right foot signal [   ] hunt6.let 2012-11-17 15:06 132K left foot signal [   ] hunt6.rit 2012-11-17 15:06 132K right foot signal [   ] hunt7.let 2012-11-17 15:06 132K left foot signal [   ] hunt7.rit 2012-11-17 15:06 132K right foot signal [   ] hunt8.let 2012-11-17 15:06 132K left foot signal [   ] hunt8.rit 2012-11-17 15:06 132K right foot signal [   ] hunt9.let 2012-11-17 15:06 132K left foot signal [   ] hunt9.rit 2012-11-17 15:06 132K right foot signal [   ] park1.let 2012-11-17 15:06 132K left foot signal [   ] park1.rit 2012-11-17 15:06 132K right foot signal [   ] park10.let 2012-11-17 15:06 132K left foot signal [   ] park10.rit 2012-11-17 15:06 132K right foot signal [   ] park11.let 2012-11-17 15:06 132K left foot signal [   ] park11.rit 2012-11-17 15:06 132K right foot signal [   ] park12.let 2012-11-17 15:06 132K left foot signal [   ] park12.rit 2012-11-17 15:06 132K right foot signal [   ] park13.let 2012-11-17 15:06 132K left foot signal [   ] park13.rit 2012-11-17 15:06 132K right foot signal [   ] park14.let 2012-11-17 15:06 132K left foot signal [   ] park14.rit 2012-11-17 15:06 132K right foot signal [   ] park15.let 2012-11-17 15:06 132K left foot signal [   ] park15.rit 2012-11-17 15:06 132K right foot signal [   ] park2.let 2012-11-17 15:06 132K left foot signal [   ] park2.rit 2012-11-17 15:06 132K right foot signal [   ] park3.let 2012-11-17 15:06 132K left foot signal [   ] park3.rit 2012-11-17 15:06 132K right foot signal [   ] park4.let 2012-11-17 15:06 132K left foot signal [   ] park4.rit 2012-11-17 15:06 132K right foot signal [   ] park5.let 2012-11-17 15:06 132K left foot signal [   ] park5.rit 2012-11-17 15:06 132K right foot signal [   ] park6.let 2012-11-17 15:06 132K left foot signal [   ] park6.rit 2012-11-17 15:06 132K right foot signal [   ] park7.let 2012-11-17 15:06 132K left foot signal [   ] park7.rit 2012-11-17 15:06 132K right foot signal [   ] park8.let 2012-11-17 15:06 132K left foot signal [   ] park8.rit 2012-11-17 15:06 132K right foot signal [   ] park9.let 2012-11-17 15:06 132K left foot signal [   ] park9.rit 2012-11-17 15:06 132K right foot signal

Questions and Comments

If you would like help understanding, using, or downloading content, please see our Frequently Asked Questions.

If you have any comments, feedback, or particular questions regarding this page, please send them to the webmaster.

Comments and issues can also be raised on PhysioNet's GitHub page.

Updated Friday, 28 October 2016 at 16:58 EDT

PhysioNet is supported by the National Institute of General Medical Sciences (NIGMS) and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under NIH grant number 2R01GM104987-09.